Protein Overview: INSI1_RAT

General Information:
Name(s) found:	INSI1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|A47112 growth response protein CL-6, insulin-induced - rat [NCBI NR] gi\|50925491\|gb\|AAH78827.1\| Insulin induced gene 1 [Rattus norvegicus] [NCBI NR] gi\|349077\|gb\|AAA40938.1\| growth response protein [Rattus norvegicus] [NCBI NR] gi\|149031423\|gb\|EDL86413.1\| insulin induced gene 1 [Rattus norvegicus] [NCBI NR] gi\|11693162\|ref\|NP_071787.1\| insulin induced gene 1 [Rattus norvegicus] [NCBI NR] gi\|1168969\|sp\|Q08755.1\|INSI1_RAT RecName: Full=Insulin-induced gene 1 protein; Short=INSIG-1; AltName: Full=Insulin-induced growth response protein CL-6; AltName: Full=Immediate-early protein CL-6 [NCBI NR] (Q08755) Insulin-induced protein 1 (Insulin-induced growth response protein CL-6) (Immediate-early protein CL-6) [Swiss-Prot] Insulin-induced gene 1 protein OS=Rattus norvegicus GN=Insig1 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):4-1421758 Insulin-induced protein 1 [hmr_yeast5_DM3-1_pombe.fasta] growth response protein (CL-6) [HMR_022704-rand.fasta] insulin induced gene 1; growth response protein (CL-6) [071204_hmrz_cont.fasta] insulin induced gene 1 [Rattus norvegicus]gi\|50925491\|gb\|AAH78827.1\| Insulin induced gene 1 [Rattus norvegicus]gi\|349077\|gb\|AAA40938.1\| growth response protein [Rattus norvegicus]gi\|1168969\|sp\|Q08755\|ISI1_RAT Insulin-induced protein 1 (Insulin-induced [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Insulin-induced gene 1 protein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_022392) growth response protein (CL-6) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Insulin-induced gene 1 protein (INSIG-1) (Insulin-induced growth response protein CL-6) (Immediate-early protein CL-6) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] insulin induced gene 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Insulin induced gene 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] growth response protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 INSULIN-INDUCED PROTEIN 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Insig1 Insulin-induced gene 1 protein [rat-ipi-250309-contam.fasta] Insulin-induced gene 1 protein OS=Rattus norvegicus GN=Insig1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	259 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [IEA] membrane [IEA] integral to membrane [IEA] endoplasmic reticulum [UNKNOWN][IEA] cellular_component [ND]
Biological Process:	negative regulation of fatty acid biosynthetic process [UNKNOWN] cranial suture morphogenesis [UNKNOWN] palate development [UNKNOWN] cholesterol biosynthetic process [UNKNOWN] cholesterol metabolic process [UNKNOWN][IEA] negative regulation of fat cell differentiation [UNKNOWN] triglyceride metabolic process [UNKNOWN] steroid metabolic process [IEA] middle ear morphogenesis [UNKNOWN] response to sterol depletion [UNKNOWN] response to peptide hormone stimulus [IEP] cellular response to insulin stimulus [IEP] ER-nuclear sterol response pathway [UNKNOWN] inner ear morphogenesis [UNKNOWN] response to estradiol stimulus [IEP] response to lipid [IEP] response to fatty acid [IEP] sterol biosynthetic process [UNKNOWN] negative regulation of steroid biosynthetic process [UNKNOWN]
Molecular Function:	protein binding [UNKNOWN] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRLHDHVWS YPSAGAARPY SLPRGMIAAA LCPQGPGAPE PEPAPRGQRE GTAGFSARPG  60
   61 SWHHDLVQRS LVLFSFGVVL ALVLNLLQIQ RNVTLFPDEV IATIFSSAWW VPPCCGTAAA 120
  121 VVGLLYPCID SHLGEPHKFK REWASVMRCI AVFVGINHAS AKLDFANNVQ LSLTLAALSL 180
  181 GLWWTFDRSR SGLGLGITIA FLATLITQFL VYNGVYQYTS PDFLYIRSWL PCIFFSGGVT 240
  241 VGNIGRQLAM GVPEKPHSD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: INSI1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: