Protein Overview: CP11A_RAT

General Information:
Name(s) found:	CP11A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|A34164 cholesterol monooxygenase (side-chain-cleaving) (EC 1.14.15.6) cytochrome P450 11A1 precursor, mitochondrial - rat [NCBI NR] gi\|8393224\|ref\|NP_058982.1\| cytochrome P450, family 11, subfamily A, polypeptide 1 [Rattus norvegicus] [NCBI NR] gi\|58177860\|gb\|AAH89100.1\| Cytochrome P450, family 11, subfamily a, polypeptide 1 [Rattus norvegicus] [NCBI NR] gi\|203639\|gb\|AAA40989.1\| cholesterol side-chain cleavage enzyme precursor (EC 1.14.15.6) [NCBI NR] gi\|203561\|gb\|AAA40958.1\| cytochrome P-450-scc [NCBI NR] gi\|149041818\|gb\|EDL95659.1\| cytochrome P450, family 11, subfamily a, polypeptide 1 [Rattus norvegicus] [NCBI NR] gi\|117262\|sp\|P14137.1\|CP11A_RAT RecName: Full=Cholesterol side-chain cleavage enzyme, mitochondrial; AltName: Full=Cytochrome P450 11A1; AltName: Full=CYPXIA1; AltName: Full=P450(scc); AltName: Full=Cholesterol desmolase; Flags: Precursor [NCBI NR] Cholesterol side-chain cleavage enzyme, mitochondrial OS=Rattus norvegicus GN=Cyp11a1 PE=2 SV=1 [Swiss-Prot] (P14137) Cytochrome P450 11A1, mitochondrial precursor (EC 1.14.15.6) (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) [Swiss-Prot] Ensembl_locations(Chr-bp):8-60203670;8-60203670 Cytochrome P450 11A1, mitochondrial precursor [hmr_yeast5_DM3-1_pombe.fasta] cytochrome P450, subfamily 11A; cytochrome P450 side-chain cleavage enzyme; cholesterol side-chain cleavage enzyme; cholesterol desmolase; cytochrome P450 11a cholesterol side; cytochrome P450 11a cholesterol side chain cleavage; cholesterol side-chain c [HMR_022704-rand.fasta] cytochrome P450, family 11, subfamily a, polypeptide 1 [Rattus norvegicus]gi\|92074\|pir\|\|A34164 cholesterol monooxygenase (side-chain-cleaving) (EC 1.14.15.6) cytochrome P450 11A1 precursor, mitochondrial - ratgi\|203639\|gb\|AAA40989.1\| cholesterol side-ch [nrdb_11152004_Chlamydomonas] (NM_017286) cytochrome P450, subfamily 11A; cytochrome P450, 11a, cholesterol side chain cleavage [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Cytochrome P450 11A1, mitochondrial precursor (CYPXIA1) (Cholesterol side-chain cleavage enzyme) (P450(scc)) (Cholesterol desmolase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cytochrome P450, family 11, subfamily a, polypeptide 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Cytochrome P450, family 11, subfamily a, polypeptide 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cholesterol side-chain cleavage enzyme precursor (EC 1.14.15.6) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cytochrome P-450-scc [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cytochrome P450, family 11, subfamily A, polypeptide 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Cytochrome P450 11A1, mitochondrial precursor (CYPXIA1) (P450(scc)) (Cholesterol side-chain cleavage enzyme) (Cholesterol desmolase) [nr-271106-contam.fasta] Cholesterol side-chain cleavage enzyme, mitochondrial OS=Rattus norvegicus GN=Cyp11a1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	526 amino acids
Gene Ontology:
Cellular Component:	mitochondrial membrane [IEA] mitochondrial crista [IDA] mitochondrion [UNKNOWN][IDA] membrane [IEA]
Biological Process:	response to organic substance [IEP] response to estrogen stimulus [IEP] granulosa cell differentiation [IEP] cerebellum development [IEP] cholesterol metabolic process [UNKNOWN][IEA] response to cAMP [IEP] response to nutrient [IEP] response to cadmium ion [IEP] steroid biosynthetic process [UNKNOWN][IMP] response to hydrogen peroxide [IMP] C21-steroid hormone biosynthetic process [UNKNOWN][IEA] mating behavior [IMP] oxidation reduction [IEA]
Molecular Function:	cholesterol monooxygenase (side-chain-cleaving) activity [UNKNOWN][IMP][TAS] cholesterol binding [IMP] metal ion binding [IEA] electron carrier activity [IEA] monooxygenase activity [IEA] heme binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAKGLCLRS VLVKSCQPFL SPVWQGPGLA TGNGAGISST NSPRSFNEIP SPGDNGWINL  60
   61 YHFLRENGTH RIHYHHMQNF QKYGPIYREK LGNMESVYIL DPKDAATLFS CEGPNPERYL 120
  121 VPPWVAYHQY YQRPIGVLFK SSDAWRKDRI VLNQEVMAPD SIKNFVPLLE GVAQDFIKVL 180
  181 HRRIKQQNSG KFSGDISDDL FRFAFESITS VVFGERLGML EEIVDPESQR FIDAVYQMFH 240
  241 TSVPMLNMPP DLFRLFRTKT WKDHAAAWDV IFSKADEYTQ NFYWDLRQKR DFSKYPGVLY 300
  301 SLLGGNKLPF KNIQANITEM LAGGVDTTSM TLQWNLYEMA HNLKVQEMLR AEVLAARRQA 360
  361 QGDMAKMVQL VPLLKASIKE TLRLHPISVT LQRYIVNDLV LRNYKIPAKT LVQVASYAMG 420
  421 RESSFFPNPN KFDPTRWLEK SQNTTHFRYL GFGWGVRQCL GRRIAELEMT IFLINVLENF 480
  481 RIEVQSIRDV GTKFNLILMP EKPIFFNFQP LKQDLGSTMP RKGDTV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.53

Protein Overview: CP11A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: