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Protein Overview: FGF14_RAT

General Information:
Name(s) found: FGF14_RAT [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Fibroblast growth factor 14 OS=Rattus norvegicus GN=Fgf14 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 247 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: [NOT]fibroblast growth factor receptor signaling pathway [UNKNOWN]
    JNK cascade [UNKNOWN]
    Molecular Function: growth factor activity [IDA]
    heparin binding [UNKNOWN]
    [NOT]fibroblast growth factor receptor binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAIASGLI RQKRQAREQH WDRPSASRRR SSPSKNRGLC NGNLVDIFSK VRIFGLKKRR  60
   61 LRRQDPQLKG IVTRLYCRQG YYLQMHPDGA LDGTKDDSTN STLFNLIPVG LRVVAIQGVK 120
  121 TGLYIAMNGE GYLYPSELFT PECKFKESVF ENYYVIYSSM LYRQQESGRA WFLGLNKEGQ 180
  181 VMKGNRVKKT KPAAHFLPKP LEVAMYREPS LHDVGETVPK AGVTPSKSTS ASAIMNGGKP 240
  241 VNKCKTT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..60] MSA 2.089996 View MSA. No confident structure predictions are available.
    2 View Details [61..247] PSI-BLAST 49.221849 Crystal structure of human FHF1b (FGF12b)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • receptor binding
    		•  4.30358117760805 bayes_pls_golite062009
  • growth factor activity
    		•  3.97089267530575 bayes_pls_golite062009
  • cytokine activity
    		•  3.76931834545338 bayes_pls_golite062009
  • binding
    		•  2.90110516688922 bayes_pls_golite062009
  • protein binding
    		•  1.94397222237906 bayes_pls_golite062009
  • fibroblast growth factor receptor binding
    		•  1.9437092554389 bayes_pls_golite062009
  • pattern binding
    		•  0.839280621598109 bayes_pls_golite062009
  • interleukin-1 receptor binding
    		•  0.8084616632765 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  0.69866345905635 bayes_pls_golite062009
  • heparin binding
    		•  0.290941670257021 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle