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Protein Overview: PPM1A_RAT

General Information:
Name(s) found: PPM1A_RAT [Swiss-Prot]
Description(s) found:
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  • gi|8394012|ref|NP_058734.1| protein phosphatase 1A, magnesium dependent, alpha isoform [Rattus norvegicus] [NCBI NR]
  • gi|206313|gb|AAA41917.1| protein phosphatase 2c [NCBI NR]
  • gi|149051426|gb|EDM03599.1| protein phosphatase 1A, magnesium dependent, alpha isoform, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|149051425|gb|EDM03598.1| protein phosphatase 1A, magnesium dependent, alpha isoform, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|129345|sp|P20650.1|PPM1A_RAT RecName: Full=Protein phosphatase 1A; AltName: Full=Protein phosphatase 2C isoform alpha; Short=PP2C-alpha; Short=IA [NCBI NR]
  • pir||A32399 phosphoprotein phosphatase (EC 3.1.3.16) 1A - rat [NCBI NR]
  • Protein phosphatase 1A OS=Rattus norvegicus GN=Ppm1a PE=1 SV=1 [Swiss-Prot]
  • Protein phosphatase 2C isoform alpha (EC 3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A) - Rattus norvegicus (Rat) [Swiss-Prot]
  • (P20650) Protein phosphatase 2C alpha isoform (EC 3.1.3.16) (PP2C-alpha) (IA) (Protein phosphatase 1A) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):6-91635930;6-91635930 Protein phosphatase 2C alpha isoform [hmr_yeast5_DM3-1_pombe.fasta]
  • protein phosphatase 1A, magnesium dependent, alpha isoform; Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform; Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform [HMR_022704-rand.fasta]
  • protein phosphatase 1A, magnesium dependent, alpha isoform [Rattus norvegicus]gi|129345|sp|P20650|P2CA_RAT Protein phosphatase 2C alpha isoform (PP2C-alpha) (IA) (Protein phosphatase 1A)gi|112147|pir||A32399 phosphoprotein phosphatase (EC 3.1.3.16) 1A - [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Protein phosphatase 2C isoform alpha [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • Tax_Id=10116 Protein phosphatase 2C alpha isoform [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta]
  • (NM_017038) protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Protein phosphatase 1A (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (IA) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • protein phosphatase 1A, magnesium dependent, alpha isoform [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • protein phosphatase 1A, magnesium dependent, alpha isoform, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • protein phosphatase 2c [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 PROTEIN PHOSPHATASE 2C ALPHA ISOFORM [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Protein phosphatase 2C isoform alpha (PP2C-alpha) (IA) (Protein phosphatase 1A) [nr-271106-contam.fasta]
  • Tax_Id=10116 Gene_Symbol=Ppm1a Protein phosphatase 1A [rat-ipi-250309-contam.fasta]
  • Protein phosphatase 1A OS=Rattus norvegicus GN=Ppm1a [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 382 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDA]
    protein serine/threonine phosphatase complex [IEA]
    voltage-gated calcium channel complex [IDA]
    neuron projection [IDA]
    Biological Process: positive regulation of transcription, DNA-dependent [UNKNOWN][IEA]
    protein amino acid dephosphorylation [UNKNOWN][IEA]
    positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN][IEA]
    Wnt receptor signaling pathway [UNKNOWN]
    positive regulation of Wnt receptor signaling pathway [UNKNOWN][IEA]
    dephosphorylation [UNKNOWN]
    Molecular Function: magnesium ion binding [IEA]
    protein serine/threonine phosphatase activity [UNKNOWN][IEA]
    phosphoprotein phosphatase activity [UNKNOWN]
    protein binding [UNKNOWN]
    protein C-terminus binding [IPI]
    manganese ion binding [IEA]
    signal transducer activity [UNKNOWN][IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAFLDKPKM EKHNAQGQGN GLRYGLSSMQ GWRVEMEDAH TAVIGLPSGL ETWSFFAVYD  60
   61 GHAGSQVAKY CCEHLLDHIT NNQDFKGSAG APSVENVKNG IRTGFLEIDE HMRVMSEKKH 120
  121 GADRSGSTAV GVLISPQHTY FINCGDSRGL LCRNRKVHFF TQDHKPSNPL EKERIQNAGG 180
  181 SVMIQRVNGS LAVSRALGDF DYKCVHGKGP TEQLVSPEPE VHDIERSEED DQFIILACDG 240
  241 IWDVMGNEEL CDFVRSRLEV TDDLEKVCNE VVDTCLYKGS RDNMSVILIC FPNAPKVSAE 300
  301 AVKKEAELDK YLENRVEEII KKQGEGVPDL VHVMRTLASE NIPSLPPGGE LASKRNVIEA 360
  361 VYNRLNPYKN DDTDSASTDD MW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle