Protein Overview: GRIK1_RAT

General Information:
Name(s) found:	GRIK1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|S19808 glutamate receptor GluR5-1 chain precursor - rat [NCBI NR] gi\|56278\|emb\|CAA77777.1\| kainate receptor [Rattus norvegicus] [NCBI NR] gi\|1169962\|sp\|P22756.3\|GRIK1_RAT RecName: Full=Glutamate receptor, ionotropic kainate 1; AltName: Full=Glutamate receptor 5; Short=GluR-5; Short=GluR5; Flags: Precursor [NCBI NR] Glutamate receptor ionotropic, kainate 1 OS=Rattus norvegicus GN=Grik1 PE=1 SV=3 [Swiss-Prot] (P22756) Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) [Swiss-Prot] Ensembl_locations(Chr-bp):None Splice isoform Glur5-2C of P22756 [hmr_yeast5_DM3-1_pombe.fasta] kainate receptor [Rattus norvegicus]gi\|1169962\|sp\|P22756\|GLK1_RAT Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5)gi\|92439\|pir\|\|S19808 glutamate receptor GluR5-1 chain precursor - rat [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Glur5-2C of Glutamate receptor, ionotropic kainate 1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] kainate receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Isoform Glur5-2C of Glutamate receptor, ionotropic kainate 1 OS=Rattus norvegicus GN=Grik1 [011711_HMR.fasta] Glutamate receptor, ionotropic kainate 1 OS=Rattus norvegicus GN=Grik1 PE=1 SV=3 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	949 amino acids
Gene Ontology:
Cellular Component:	presynaptic membrane [UNKNOWN][IEA] receptor complex [IDA] neuronal cell body [IDA] synapse [IEA] ionotropic glutamate receptor complex [IDA] plasma membrane [UNKNOWN][IMP] dendrite [UNKNOWN][IDA] terminal button [IDA] postsynaptic membrane [IEA] membrane [UNKNOWN][IEA] integral to membrane [IEA] cell junction [IEA] kainate selective glutamate receptor complex [UNKNOWN][IEA]
Biological Process:	regulation of excitatory postsynaptic membrane potential [UNKNOWN][IEA] positive regulation of synaptic transmission, GABAergic [UNKNOWN][IDA] positive regulation of gamma-aminobutyric acid secretion [UNKNOWN][IEA] nervous system development [IMP] synaptic transmission [TAS] ion transport [IEA] negative regulation of synaptic transmission, GABAergic [IDA] regulation of membrane potential [UNKNOWN] regulation of synaptic plasticity [TAS] behavioral response to pain [UNKNOWN][IEA] regulation of inhibitory postsynaptic membrane potential [UNKNOWN][IEA] negative regulation of synaptic transmission, glutamatergic [UNKNOWN][IDA] ionotropic glutamate receptor signaling pathway [IDA] membrane depolarization [UNKNOWN] regulation of short-term neuronal synaptic plasticity [IDA] adult behavior [UNKNOWN][IEA] synaptic transmission, glutamatergic [UNKNOWN]
Molecular Function:	ion channel activity [IEA] protein binding [UNKNOWN][IEA] kainate selective glutamate receptor activity [UNKNOWN][IDA] protein homodimerization activity [IDA] drug binding [IDA] voltage-gated cation channel activity [IMP] glutamate binding [IDA] receptor activity [IEA] ionotropic glutamate receptor activity [IDA][IEA] extracellular-glutamate-gated ion channel activity [IDA][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERSTVLIQP GLWTRDTSWT LLYFLCYILP QTSPQVLRIG GIFETVENEP VNVEELAFKF  60
   61 AVTSINRNRT LMPNTTLTYD IQRINLFDSF EASRRACDQL ALGVAALFGP SHSSSVSAVQ 120
  121 SICNALEVPH IQTRWKHPSV DSRDLFYINL YPDYAAISRA VLDLVLYYNW KTVTVVYEDS 180
  181 TGLIRLQELI KAPSRYNIKI KIRQLPPANK DAKPLLKEMK KSKEFYVIFD CSHETAAEIL 240
  241 KQILFMGMMT EYYHYFFTTL DLFALDLELY RYSGVNMTGF RKLNIDNPHV SSIIEKWSME 300
  301 RLQAPPRPET GLLDGMMTTE AALMYDAVYM VAIASHRASQ LTVSSLQCHR HKPCALGPRF 360
  361 MNLIKEARWD GLTGRITFNK TDGLRKDFDL DIISLKEEGT EKASGEVSKH LYKVWKKIGI 420
  421 WNSNSGLNMT DGNRDRSNNI TDSLANRTLI VTTILEEPYV MYRKSDKPLY GNDRFEAYCL 480
  481 DLLKELSNIL GFLYDVKLVP DGKYGAQNDK GEWNGMVKEL IDHRADLAVA PLTITYVREK 540
  541 VIDFSKPFMT LGISILYRKP NGTNPGVFSF LNPLSPDIWM YVLLACLGVS CVLFVIARFT 600
  601 PYEWYNPHPC NPDSDVVENN FTLLNSFWFG VGALMQQGSE LMPKALSTRI VGGIWWFFTL 660
  661 IIISSYTANL AAFLTVERME SPIDSADDLA KQTKIEYGAV RDGSTMTFFK KSKISTYEKM 720
  721 WAFMSSRQQS ALVKNSDEGI QRVLTTDYAL LMESTSIEYV TQRNCNLTQI GGLIDSKGYG 780
  781 VGTPIGSPYR DKITIAILQL QEEGKLHMMK EKWWRGNGCP EEDSKEASAL GVENIGGIFI 840
  841 VLAAGLVLSV FVAIGEFLYK SRKNNDVEQK GKSSRLRFYF RNKVRFHGSK KESLGVEKCL 900
  901 SFNAIMEELG ISLKNQKKLK KKSRTKGKSS FTSILTCHQR RTQRKETVA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GRIK1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: