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Protein Overview: CIRBP_RAT

General Information:
Name(s) found: CIRBP_RAT [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Cold-inducible RNA-binding protein OS=Rattus norvegicus GN=Cirbp PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 172 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN]
    stress granule [IEA]
    cytoplasm [UNKNOWN]
    Biological Process: response to cold [IEP]
    stress granule assembly [IEA]
    positive regulation of translation [UNKNOWN]
    mRNA stabilization [UNKNOWN]
    response to UV [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    nucleic acid binding [IEA]
    protein binding [UNKNOWN]
    translation repressor activity [IEA]
    SSU rRNA binding [UNKNOWN]
    mRNA 3'-UTR binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASDEGKLFV GGLSFDTNEQ ALEQVFSKYG QISEVVVVKD RETQRSRGFG FVTFENIDDA  60
   61 KDAMMAMNGK SVDGRQIRVD QAGKSSDNRS RGYRGGSAGG RGFFRGGRSR GRGFSRGGGD 120
  121 RGYGGGRFES RSGGYGGSRD YYASRSQGGS YGYRSSGGSY RDSYDSYATH NE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..172] PSI-BLAST 23.522879 Solution structure of RRM domain in A18 hnRNP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.3641419747005 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.652211965253825 bayes_pls_golite062009
  • RNA binding
    		•  0.498012521772139 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle