Protein Overview: GPC3_RAT

General Information:
Name(s) found:	GPC3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6980976\|ref\|NP_036906.1\| glypican 3 [Rattus norvegicus] [NCBI NR] gi\|205800\|gb\|AAA41735.1\| intestinal protein OCI-5 [NCBI NR] gi\|129025\|sp\|P13265.1\|GPC3_RAT RecName: Full=Glypican-3; AltName: Full=Intestinal protein OCI-5; Flags: Precursor [NCBI NR] pir\|\|A30814 development-specific protein OCI-5 - rat [NCBI NR] Glypican-3 OS=Rattus norvegicus GN=Gpc3 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):None Glypican-3 precursor [hmr_yeast5_DM3-1_pombe.fasta] glypican 3 [HMR_022704-rand.fasta] glypican 3 [Rattus norvegicus]gi\|129025\|sp\|P13265\|GPC3_RAT Glypican-3 precursor (Intestinal protein OCI-5)gi\|111579\|pir\|\|A30814 development-specific protein OCI-5 - ratgi\|205800\|gb\|AAA41735.1\| intestinal protein OCI-5 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Glypican-3 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012774) glypican 3 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Glypican-3 precursor (Intestinal protein OCI-5) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glypican 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] intestinal protein OCI-5 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 GLYPICAN-3 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Gpc3 Glypican-3 [rat-ipi-250309-contam.fasta] Glypican-3 OS=Rattus norvegicus GN=Gpc3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	597 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] extracellular region [IEA] proteinaceous extracellular matrix [IEA] plasma membrane [IEA] lysosome [UNKNOWN][IEA] anchored to plasma membrane [UNKNOWN][IEA]
Biological Process:	negative regulation of growth [UNKNOWN][IEA] positive regulation of BMP signaling pathway [UNKNOWN][IEA] branching involved in ureteric bud morphogenesis [UNKNOWN][IEA] negative regulation of cell proliferation [UNKNOWN][IEA] positive regulation of endocytosis [UNKNOWN][IEA] body morphogenesis [UNKNOWN][IEA] positive regulation of protein catabolic process [UNKNOWN][IEA] negative regulation of smoothened signaling pathway [UNKNOWN][IEA] organ morphogenesis [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN][IEA] heparan sulfate proteoglycan binding [IEA] peptidyl-dipeptidase inhibitor activity [UNKNOWN][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGTVRTACL LVAMLLGLGC LGQAQPPPPP DATCHQVRSF FQRLQPGLKW VPETPVPGSD  60
   61 LQVCLPKGPT CCSRKMEEKY QLTARLNMEQ LLQSASMELK FLIIQNAAVF QEAFEIVVRH 120
  121 AKNYTNAMFK NNYPSLTPQA FEFVGEFFTD VSLYILGSDI NVDDMVNELF DSLFPVIYTQ 180
  181 MMNPGLPESV LDINECLRGA RRDLKVFGSF PKLIMTQVSK SLQVTRIFLQ ALNLGIEVIN 240
  241 TTDHLKFSKD CGRMLTRMWY CSYCQGLMMV KPCGGYCNVV MQGCMAGVVE IDKYWREYIL 300
  301 SLEELVNGMY RIYDMENVLL GLFSTIHDSI QYVQKNGGKL TTTIGKLCAH SQQRQYRSAY 360
  361 YPEDLFIDKK VLKVARVEHE ETLSSRRREL IQKLKSFISF YSALPGYICS HSPVAENDTL 420
  421 CWNGQELVER YSQKAARNGM KNQFNLHELK MKGPEPVVSQ IIDKLKHINQ LLRTMSVPKG 480
  481 KVVDKSLDEE GLESGDCGDD EDECIGSSGD GMMKVKNQLR FLAELAYDLD VDDAPGNKQH 540
  541 GNQKDNEITT SHSVGNMPSP LKILISVAIY VACFFSWCTD LPCPCLCCPA APCGPPT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GPC3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: