Protein Overview: VATB2_RAT

General Information:
Name(s) found:	VATB2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|55716047\|gb\|AAH85714.1\| ATPase, H transporting, lysosomal V1 subunit B2 [Rattus norvegicus] [NCBI NR] gi\|51338689\|sp\|P62815.1\|VATB2_RAT RecName: Full=V-type proton ATPase subunit B, brain isoform; Short=V-ATPase subunit B 2; AltName: Full=Vacuolar proton pump subunit B 2; AltName: Full=Endomembrane proton pump 58 kDa subunit [NCBI NR] gi\|2058354\|emb\|CAA73183.1\| vacuolar adenosine triphosphatase subunit B [Rattus norvegicus] [NCBI NR] gi\|17105370\|ref\|NP_476561.1\| vacuolar H+ATPase B2 [Rattus norvegicus] [NCBI NR] gi\|149029422\|gb\|EDL84666.1\| ATPase, H transporting, lysosomal V1 subunit B2, isoform CRA_a [Rattus norvegicus] [NCBI NR] V-type proton ATPase subunit B, brain isoform OS=Rattus norvegicus GN=Atp6v1b2 PE=1 SV=1 [Swiss-Prot] (P62815) Vacuolar ATP synthase subunit B, brain isoform (EC 3.6.3.14) (V-ATPase B2 subunit) (Vacuolar proton pump B isoform 2) (Endomembrane proton pump 58 kDa subunit) [Swiss-Prot] Ensembl_locations(Chr-bp):16-22036813 Vacuolar ATP synthase subunit B, brain isoform [hmr_yeast5_DM3-1_pombe.fasta] ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa, isoform 2 [HMR_022704-rand.fasta] ATPase, H+ transporting, V1 subunit B, isoform 2 [Mus musculus]gi\|19705578\|ref\|NP_031535.2\| ATPase, H+ transporting, V1 subunit B, isoform 2 [Mus musculus]gi\|17105370\|ref\|NP_476561.1\| ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Vacuolar ATP synthase subunit B, brain isoform [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_057213) ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa, isoform 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Vacuolar ATP synthase subunit B, brain isoform (V-ATPase subunit B 2) (Vacuolar proton pump subunit B 2) (Endomembrane proton pump 58 kDa subunit) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] vacuolar H+ATPase B2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ATPase, H transporting, lysosomal V1 subunit B2, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ATPase, H transporting, lysosomal V1 subunit B2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] vacuolar adenosine triphosphatase subunit B [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 VACUOLAR ATP SYNTHASE SUBUNIT B, BRAIN ISOFORM [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Vacuolar ATP synthase subunit B, brain isoform (V-ATPase B2 subunit) (Vacuolar proton pump B isoform 2) (Endomembrane proton pump 58 kDa subunit) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Atp6v1b2 V-type proton ATPase subunit B, brain isoform [rat-ipi-250309-contam.fasta] V-type proton ATPase subunit B, brain isoform OS=Rattus norvegicus GN=Atp6v1b2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	511 amino acids
Gene Ontology:
Cellular Component:	melanosome [IEA] intracellular membrane-bounded organelle [UNKNOWN] integral to membrane [IDA] cytosol [ISS] Golgi apparatus [UNKNOWN][IEA] proton-transporting V-type ATPase, V1 domain [IEA] plasma membrane [ISS]
Biological Process:	ion transport [IEA] proton transport [IEA] ATP metabolic process [IEA] vacuolar acidification [TAS] regulation of cellular pH [TAS] ATP synthesis coupled proton transport [IEA]
Molecular Function:	ATP binding [IEA] proton-transporting ATPase activity, rotational mechanism [IEA] hydrolase activity [IEA] hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances [IEA] hydrogen ion transporting ATP synthase activity, rotational mechanism [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRAMRGIV NGAAPELPVP TGGPMAGARE QALAVSRNYL SQPRLTYKTV SGVNGPLVIL  60
   61 DHVKFPRYAE IVHLTLPDGT KRSGQVLEVS GSKAVVQVFE GTSGIDAKKT SCEFTGDILR 120
  121 TPVSEDMLGR VFNGSGKPID RGPVVLAEDF LDIMGQPINP QCRIYPEEMI QTGISAIDGM 180
  181 NSIARGQKIP IFSAAGLPHN EIAAQICRQA GLVKKSKDVV DYSEENFAIV FAAMGVNMET 240
  241 ARFFKSDFEE NGSMDNVCLF LNLANDPTIE RIITPRLALT TAEFLAYQCE KHVLVILTDM 300
  301 SSYAEALREV SAAREEVPGR RGFPGYMYTD LATIYERAGR VEGRNGSITQ IPILTMPNDD 360
  361 ITHPIPDLTG YITEGQIYVD RQLHNRQIYP PINVLPSLSR LMKSAIGEGM TRKDHADVSN 420
  421 QLYACYAIGK DVQAMKAVVG EEALTSDDLL YLEFLQKFEK NFITQGPYEN RTVYETLDIG 480
  481 WQLLRIFPKE MLKRIPQSTL SEFYPRDSAK H

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: VATB2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: