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Protein Overview: LEG1_RAT

General Information:
Name(s) found: LEG1_RAT [Swiss-Prot]
Description(s) found:
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  • gi|9845261|ref|NP_063969.1| lectin, galactoside-binding, soluble, 1 [Rattus norvegicus] [NCBI NR]
  • pir||LNRTGB beta-galactoside-binding lectin - rat [NCBI NR]
  • gi|34849649|gb|AAH58476.1| Lectin, galactoside-binding, soluble, 1 [Rattus norvegicus] [NCBI NR]
  • gi|203162|gb|AAA40822.1| beta-galactoside-binding protein [NCBI NR]
  • gi|149065965|gb|EDM15838.1| lectin, galactose binding, soluble 1 [Rattus norvegicus] [NCBI NR]
  • gi|126177|sp|P11762.2|LEG1_RAT RecName: Full=Galectin-1; AltName: Full=Lectin galactoside-binding soluble 1; AltName: Full=Beta-galactoside-binding lectin L-14-I; Short=Lactose-binding lectin 1; AltName: Full=S-Lac lectin 1; AltName: Full=Galaptin; AltNam [NCBI NR]
  • Galectin-1 OS=Rattus norvegicus GN=Lgals1 PE=1 SV=2 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):7-106803705 beta-galactoside-binding lectin [hmr_yeast5_DM3-1_pombe.fasta]
  • beta-galactoside-binding lectin [HMR_022704-rand.fasta]
  • beta-galactoside-binding lectin [Rattus norvegicus]gi|34849649|gb|AAH58476.1| Beta-galactoside-binding lectin [Rattus norvegicus]gi|476495|pir||LNRTGB beta-galactoside-binding lectin - ratgi|126177|sp|P11762|LEG1_RAT Galectin-1 (Beta-galactoside-bindin [nrdb_11152004_Chlamydomonas]
  • (NM_019904) beta-galactoside-binding lectin [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Galectin-1 (Lectin galactoside-binding soluble 1) (Beta-galactoside-binding lectin L-14-I) (Lactose-binding lectin 1) (S-Lac lectin 1) (Galaptin) (14 kDa lectin) (RL 14.5) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • lectin, galactose binding, soluble 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Lectin, galactose binding, soluble 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • beta-galactoside-binding protein [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 BETA-GALACTOSIDE-BINDING LECTIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • lectin, galactoside-binding, soluble, 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta]
  • beta-galactoside-binding lectin [Rattus norvegicus] [nr-271106-contam.fasta]
  • Tax_Id=10116 Gene_Symbol=Lgals1 Galectin-1 [rat-ipi-250309-contam.fasta]
  • Galectin-1 OS=Rattus norvegicus GN=Lgals1 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 135 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    extracellular space [UNKNOWN][IEA]
    cytoplasm [IDA]
    extracellular region [IEA]
    proteinaceous extracellular matrix [IEA]
    intracellular [UNKNOWN][IEA]
    cell surface [IDA]
    Biological Process: negative regulation of cell-substrate adhesion [IDA]
    negative regulation of neuron projection development [IMP]
    cellular response to glucose stimulus [IEP]
    response to drug [IEP]
    positive regulation of erythrocyte aggregation [IDA]
    multicellular organismal response to stress [IEP]
    positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN][IEA]
    myoblast differentiation [UNKNOWN][IEA]
    response to axon injury [IEP]
    cellular response to organic cyclic substance [IEP]
    Molecular Function: protein binding [UNKNOWN]
    protein homodimerization activity [IDA]
    sugar binding [IEA]
    galactoside binding [IEA]
    lactose binding [IDA]
    glycoprotein binding [IPI]
    signal transducer activity [UNKNOWN][IEA]
    laminin binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MACGLVASNL NLKPGECLKV RGELAPDAKS FVLNLGKDSN NLCLHFNPRF NAHGDANTIV  60
   61 CNSKDDGTWG TEQRETAFPF QPGSITEVCI TFDQADLTIK LPDGHEFKFP NRLNMEAINY 120
  121 MAADGDFKIK CVAFE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] PSI-BLAST 42.39794 X-RAY CRYSTAL STRUCTURE OF HUMAN GALECTIN-1


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle