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Protein Overview: LDHA_RAT

General Information:
Name(s) found: LDHA_RAT [Swiss-Prot]
Description(s) found:
Found 22 descriptions.
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  • L-lactate dehydrogenase A chain OS=Rattus norvegicus GN=Ldha PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 332 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [IDA]
    cytoplasm [IEA]
    mitochondrion [UNKNOWN]
    flagellum [UNKNOWN]
    cytosol [UNKNOWN]
    Biological Process: response to estrogen stimulus [IEP]
    glycolysis [IEA]
    post-embryonic organ development [IEP]
    response to cAMP [IEP]
    response to nutrient [IEP]
    lactate metabolic process [IDA]
    response to organic cyclic substance [IEP]
    response to hydrogen peroxide [IEP]
    response to glucose stimulus [IEP]
    cellular response to extracellular stimulus [UNKNOWN]
    response to hypoxia [IEP]
    cellular carbohydrate metabolic process [IEA]
    response to drug [IEP]
    positive regulation of apoptosis [IDA]
    NAD metabolic process [IDA]
    oxidation reduction [IEA]
    Molecular Function: lactate dehydrogenase activity [IDA]
    identical protein binding [IDA]
    L-lactate dehydrogenase activity [UNKNOWN][IDA]
    protein binding [UNKNOWN][IPI]
    oxidoreductase activity [IEA]
    NAD or NADH binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALKDQLIV NLLKEEQVPQ NKITVVGVGA VGMACAISIL MKDLADELAL VDVIEDKLKG  60
   61 EMMDLQHGSL FLKTPKIVSS KDYSVTANSK LVIITAGARQ QEGESRLNLV QRNVNIFKFI 120
  121 IPNVVKYSPQ CKLLIVSNPV DILTYVAWKI SGFPKNRVIG SGCNLDSARF RYLMGERLGV 180
  181 HPLSCHGWVL GEHGDSSVPV WSGVNVAGVS LKSLNPQLGT DADKEQWKDV HKQVVDSAYE 240
  241 VIKLKGYTSW AIGLSVADLA ESIMKNLRRV HPISTMIKGL YGIKEDVFLS VPCILGQNGI 300
  301 SDVVKVTLTP DEEARLKKSA DTLWGIQKEL QF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.74

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle