Protein Overview: GCYA3_RAT

General Information:
Name(s) found:	GCYA3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8393504\|ref\|NP_058786.1\| guanylate cyclase 1, soluble, alpha 3 [Rattus norvegicus] [NCBI NR] pir\|\|OYRTA1 guanylate cyclase (EC 4.6.1.2), soluble, alpha-1 chain - rat [NCBI NR] gi\|204278\|gb\|AAA41206.1\| guanylate cyclase [NCBI NR] gi\|1655847\|gb\|AAB17953.1\| soluble guanylyl cyclase alpha 1 subunit [Rattus norvegicus] [NCBI NR] gi\|118060\|sp\|P19686.1\|GCYA3_RAT RecName: Full=Guanylate cyclase soluble subunit alpha-3; Short=GCS-alpha-3; AltName: Full=Soluble guanylate cyclase large subunit; AltName: Full=GCS-alpha-1 [NCBI NR] Guanylate cyclase soluble subunit alpha-3 OS=Rattus norvegicus GN=Gucy1a3 PE=1 SV=1 [Swiss-Prot] (P19686) Guanylate cyclase soluble, alpha-3 chain (EC 4.6.1.2) (GCS-alpha-3) (Soluble guanylate cyclase large subunit) (GCS-alpha-1) [Swiss-Prot] Ensembl_locations(Chr-bp):2-169044460;2-169044460;2-169044460;2-169044460 Guanylate cyclase soluble, alpha-3 chain [hmr_yeast5_DM3-1_pombe.fasta] guanylate cyclase 1, soluble, alpha 3; Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase); Guanylate cyclase soluble alpha 1 (GTP pyrophosphate - lyase); soluble guanylate cyclase [HMR_022704-rand.fasta] guanylate cyclase 1, soluble, alpha 3; Guanylate cyclase soluble alpha 1 (GTP pyrophosphate - lyase); soluble guanylate cyclase; Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase) [071204_hmrz_cont.fasta] guanylate cyclase 1, soluble, alpha 3 [Rattus norvegicus]gi\|1655847\|gb\|AAB17953.1\| soluble guanylyl cyclase alpha 1 subunit [Rattus norvegicus]gi\|118060\|sp\|P19686\|CYG3_RAT Guanylate cyclase soluble, alpha-3 chain (GCS-alpha-3) (Soluble guanylate cyclase [nrdb_11152004_Chlamydomonas] (NM_017090) guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Guanylate cyclase soluble subunit alpha-3 (GCS-alpha-3) (Soluble guanylate cyclase large subunit) (GCS-alpha-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] soluble guanylyl cyclase alpha 1 subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] guanylate cyclase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 GUANYLATE CYCLASE SOLUBLE, ALPHA-3 CHAIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] guanylate cyclase 1, soluble, alpha 3 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Gucy1a3 Guanylate cyclase soluble subunit alpha-3 [rat-ipi-250309-contam.fasta] Guanylate cyclase soluble subunit alpha-3 OS=Rattus norvegicus GN=Gucy1a3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	690 amino acids
Gene Ontology:
Cellular Component:	guanylate cyclase complex, soluble [IDA][TAS] cytoplasm [IEA] protein complex [IDA]
Biological Process:	cGMP biosynthetic process [UNKNOWN][IDA] response to defense-related host nitric oxide production [UNKNOWN][IEA] nitric oxide mediated signal transduction [IDA] positive regulation of cGMP biosynthetic process [UNKNOWN][IEA] relaxation of vascular smooth muscle [UNKNOWN][IEA] response to organic cyclic substance [IEP] regulation of blood pressure [UNKNOWN][IEA] response to herbicide [IEP]
Molecular Function:	nucleotide binding [IEA] GTP binding [IDA] protein heterodimerization activity [IDA] ion binding [IDA] guanylate cyclase activity [IDA][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFCRKFKDLK ITGECPFSLL APGQVPTEPI EEVAGVSESC QATLPTCQEF AENAEGSHPQ  60
   61 RKTSRNRVYL HTLAESIGKL IFPEFERLNL ALQRTLAKHK IKENRNSSEK EDLERIIAEE 120
  121 AIAAGVPVEV LKDSLGEELF KICYEEDEHI LGVVGGTLKD FLNSFSTLLK QSSHCQEAER 180
  181 RGRLEDASIL CLDKDQDFLN VYYFFPKRTT ALLLPGIIKA AARILYESHV EVSLMPPCFR 240
  241 SECTEFVNQP YLLYSVHVKS TKPSLSPGKP QSSLVIPTSL FCKTFPFHFM LDRDLAILQL 300
  301 GNGIRRLVNK RDFQGKPNFE EFFEILTPKI NQTFSGIMTM LNMQFVIRVR RWDNLVKKSS 360
  361 RVMDLKGQMI YIVESSAILF LGSPCVDRLE DFTGRGLYLS DIPIHNALRD VVLIGEQARA 420
  421 QDGLKKRLGK LKATLEHAHQ ALEEEKKKTV DLLCSIFPSE VAQQLWQGQI VQAKKFNEVT 480
  481 MLFSDIVGFT AICSQCSPLQ VITMLNALYT RFDQQCGELD VYKVETIGDA YCVAGGLHRE 540
  541 SDTHAVQIAL MALKMMELSN EVMSPHGEPI KMRIGLHSGS VFAGVVGVKM PRYCLFGNNV 600
  601 TLANKFESCS VPRKINVSPT TYRLLKDCPG FVFTPRSREE LPPNFPSDIP GICHFLDAYQ 660
  661 HQGPNSKPWF QQKDAEDGNA NFLGKASGVD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.89

Protein Overview: GCYA3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: