Protein Overview: ACHB2_RAT

General Information:
Name(s) found:	ACHB2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9506485\|ref\|NP_062170.1\| neuronal nicotinic acetylcholine receptor beta 2 [Rattus norvegicus] [NCBI NR] gi\|6226548\|sp\|P12390.2\|ACHB2_RAT RecName: Full=Neuronal acetylcholine receptor subunit beta-2; AltName: Full=Neuronal acetylcholine receptor non-alpha-1 chain; Short=N-alpha 1; Flags: Precursor [NCBI NR] gi\|46371171\|gb\|AAS90354.1\| neuronal nicotinic acetylcholine receptor beta2 subunit [Rattus norvegicus] [NCBI NR] gi\|3892044\|gb\|AAC78724.1\| nicotinic acetylcholine receptor beta 2 subunit [Rattus norvegicus] [NCBI NR] gi\|149048038\|gb\|EDM00614.1\| cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) [Rattus norvegicus] [NCBI NR] (P12390) Neuronal acetylcholine receptor protein, beta-2 chain precursor (Neuronal acetylcholine receptor non-alpha-1 chain) (N-alpha 1) [Swiss-Prot] Neuronal acetylcholine receptor subunit beta-2 OS=Rattus norvegicus GN=Chrnb2 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):2-181567268 Neuronal acetylcholine receptor protein, beta-2 chain precursor [hmr_yeast5_DM3-1_pombe.fasta] cholinergic receptor, nicotinic, beta polypeptide 2; cholinergic receptor, nicotinic, beta subunit 2; cholinergic receptor nicotinic beta subunit 2 [HMR_022704-rand.fasta] cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) [Rattus norvegicus]gi\|3892044\|gb\|AAC78724.1\| nicotinic acetylcholine receptor beta 2 subunit [Rattus norvegicus]gi\|6226548\|sp\|P12390\|ACHN_RAT Neuronal acetylcholine receptor protein, beta-2 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Neuronal acetylcholine receptor protein, beta-2 subunit precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_019297) cholinergic receptor, nicotinic, beta polypeptide 2; cholinergic receptor, nicotinic, beta subunit 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Neuronal acetylcholine receptor protein, beta-2 chain precursor [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Neuronal acetylcholine receptor subunit beta-2 precursor (Neuronal acetylcholine receptor non-alpha-1 chain) (N-alpha 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] neuronal nicotinic acetylcholine receptor beta 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] neuronal nicotinic acetylcholine receptor beta2 subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] nicotinic acetylcholine receptor beta 2 subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, BETA-2 CHAIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Neuronal acetylcholine receptor protein subunit beta-2 precursor (Neuronal acetylcholine receptor non-alpha-1 chain) (N-alpha 1) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Chrnb2 Neuronal acetylcholine receptor subunit beta-2 [rat-ipi-250309-contam.fasta] Neuronal acetylcholine receptor subunit beta-2 OS=Rattus norvegicus GN=Chrnb2 [011711_HMR.fasta] Neuronal acetylcholine receptor subunit beta-2 OS=Rattus norvegicus GN=Chrnb2 PE=2 SV=2 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	500 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] postsynaptic membrane [IEA] external side of plasma membrane [UNKNOWN][IEA] integral to membrane [IEA] cell junction [IEA] nicotinic acetylcholine-gated receptor-channel complex [UNKNOWN][IDA] synapse [IEA] plasma membrane [UNKNOWN][IDA]
Biological Process:	synaptic transmission, cholinergic [IMP] central nervous system neuron axonogenesis [UNKNOWN] synaptic transmission involved in micturition [UNKNOWN][IEA] central nervous system projection neuron axonogenesis [UNKNOWN][IEA] visual learning [UNKNOWN][IEA] protein heterooligomerization [IDA] B cell activation [UNKNOWN][IEA] learning [UNKNOWN] associative learning [UNKNOWN] lateral geniculate nucleus development [UNKNOWN][IEA] memory [UNKNOWN][IEA] regulation of dendrite morphogenesis [UNKNOWN][IEA] optic nerve morphogenesis [UNKNOWN][IEA] sensory perception of sound [UNKNOWN][IEA] response to ethanol [UNKNOWN][IEA] ion transport [IEA] response to hypoxia [UNKNOWN][IEA] locomotory behavior [UNKNOWN][IEA] cognition [UNKNOWN][IEA] smooth muscle contraction [UNKNOWN][IEA] calcium ion transport [UNKNOWN][IEA] regulation of action potential [UNKNOWN] neurological system process [UNKNOWN] regulation of synaptic transmission, dopaminergic [UNKNOWN] regulation of synaptogenesis [UNKNOWN][IEA] positive regulation of synaptic transmission, dopaminergic [UNKNOWN][IEA] regulation of dopamine secretion [UNKNOWN] social behavior [UNKNOWN][IEA] negative regulation of action potential [UNKNOWN][IEA] behavioral response to nicotine [UNKNOWN][IEA] signal transduction [UNKNOWN][IEA] response to cocaine [UNKNOWN][IEA] regulation of circadian sleep/wake cycle, REM sleep [UNKNOWN][IEA] response to nicotine [UNKNOWN][IMP] visual perception [UNKNOWN][IEA] vestibulocochlear nerve development [UNKNOWN][IEA] conditioned taste aversion [UNKNOWN][IEA] regulation of membrane potential [UNKNOWN] regulation of circadian sleep/wake cycle, non-REM sleep [UNKNOWN][IEA] regulation of dopamine metabolic process [UNKNOWN][IEA] sensory perception of pain [UNKNOWN][IEA] positive regulation of B cell proliferation [UNKNOWN] positive regulation of dopamine secretion [UNKNOWN][IEA] membrane depolarization [UNKNOWN][IEA]
Molecular Function:	ion channel activity [IEA] nicotinic acetylcholine-activated cation-selective channel activity [IC][UNKNOWN][IDA] protein binding [UNKNOWN][IEA] acetylcholine receptor activity [UNKNOWN][IEA] drug binding [IDA] extracellular ligand-gated ion channel activity [IEA] acetylcholine binding [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
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    1 MAGHSNSMAL FSFSLLWLCS GVLGTDTEER LVEHLLDPSR YNKLIRPATN GSELVTVQLM  60
   61 VSLAQLISVH EREQIMTTNV WLTQEWEDYR LTWKPEDFDN MKKVRLPSKH IWLPDVVLYN 120
  121 NADGMYEVSF YSNAVVSYDG SIFWLPPAIY KSACKIEVKH FPFDQQNCTM KFRSWTYDRT 180
  181 EIDLVLKSDV ASLDDFTPSG EWDIIALPGR RNENPDDSTY VDITYDFIIR RKPLFYTINL 240
  241 IIPCVLITSL AILVFYLPSD CGEKMTLCIS VLLALTVFLL LISKIVPPTS LDVPLVGKYL 300
  301 MFTMVLVTFS IVTSVCVLNV HHRSPTTHTM APWVKVVFLE KLPTLLFLQQ PRHRCARQRL 360
  361 RLRRRQRERE GAGALFFREG PAADPCTCFV NPASVQGLAG AFRAEPTAAG PGRSVGPCSC 420
  421 GLREAVDGVR FIADHMRSED DDQSVREDWK YVAMVIDRLF LWIFVFVCVF GTVGMFLQPL 480
  481 FQNYTATTFL HPDHSAPSSK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ACHB2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: