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Protein Overview: ACHB2_RAT

General Information:
Name(s) found: ACHB2_RAT [Swiss-Prot]
Description(s) found:
Found 23 descriptions.
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  • Neuronal acetylcholine receptor subunit beta-2 OS=Rattus norvegicus GN=Chrnb2 PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 500 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDA]
    postsynaptic membrane [IEA]
    external side of plasma membrane [UNKNOWN][IEA]
    integral to membrane [IEA]
    cell junction [IEA]
    nicotinic acetylcholine-gated receptor-channel complex [UNKNOWN][IDA]
    synapse [IEA]
    plasma membrane [UNKNOWN][IDA]
    Biological Process: synaptic transmission, cholinergic [IMP]
    central nervous system neuron axonogenesis [UNKNOWN]
    synaptic transmission involved in micturition [UNKNOWN][IEA]
    central nervous system projection neuron axonogenesis [UNKNOWN][IEA]
    visual learning [UNKNOWN][IEA]
    protein heterooligomerization [IDA]
    B cell activation [UNKNOWN][IEA]
    learning [UNKNOWN]
    associative learning [UNKNOWN]
    lateral geniculate nucleus development [UNKNOWN][IEA]
    memory [UNKNOWN][IEA]
    regulation of dendrite morphogenesis [UNKNOWN][IEA]
    optic nerve morphogenesis [UNKNOWN][IEA]
    sensory perception of sound [UNKNOWN][IEA]
    response to ethanol [UNKNOWN][IEA]
    ion transport [IEA]
    response to hypoxia [UNKNOWN][IEA]
    locomotory behavior [UNKNOWN][IEA]
    cognition [UNKNOWN][IEA]
    smooth muscle contraction [UNKNOWN][IEA]
    calcium ion transport [UNKNOWN][IEA]
    regulation of action potential [UNKNOWN]
    neurological system process [UNKNOWN]
    regulation of synaptic transmission, dopaminergic [UNKNOWN]
    regulation of synaptogenesis [UNKNOWN][IEA]
    positive regulation of synaptic transmission, dopaminergic [UNKNOWN][IEA]
    regulation of dopamine secretion [UNKNOWN]
    social behavior [UNKNOWN][IEA]
    negative regulation of action potential [UNKNOWN][IEA]
    behavioral response to nicotine [UNKNOWN][IEA]
    signal transduction [UNKNOWN][IEA]
    response to cocaine [UNKNOWN][IEA]
    regulation of circadian sleep/wake cycle, REM sleep [UNKNOWN][IEA]
    response to nicotine [UNKNOWN][IMP]
    visual perception [UNKNOWN][IEA]
    vestibulocochlear nerve development [UNKNOWN][IEA]
    conditioned taste aversion [UNKNOWN][IEA]
    regulation of membrane potential [UNKNOWN]
    regulation of circadian sleep/wake cycle, non-REM sleep [UNKNOWN][IEA]
    regulation of dopamine metabolic process [UNKNOWN][IEA]
    sensory perception of pain [UNKNOWN][IEA]
    positive regulation of B cell proliferation [UNKNOWN]
    positive regulation of dopamine secretion [UNKNOWN][IEA]
    membrane depolarization [UNKNOWN][IEA]
    Molecular Function: ion channel activity [IEA]
    nicotinic acetylcholine-activated cation-selective channel activity [IC][UNKNOWN][IDA]
    protein binding [UNKNOWN][IEA]
    acetylcholine receptor activity [UNKNOWN][IEA]
    drug binding [IDA]
    extracellular ligand-gated ion channel activity [IEA]
    acetylcholine binding [UNKNOWN][IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGHSNSMAL FSFSLLWLCS GVLGTDTEER LVEHLLDPSR YNKLIRPATN GSELVTVQLM  60
   61 VSLAQLISVH EREQIMTTNV WLTQEWEDYR LTWKPEDFDN MKKVRLPSKH IWLPDVVLYN 120
  121 NADGMYEVSF YSNAVVSYDG SIFWLPPAIY KSACKIEVKH FPFDQQNCTM KFRSWTYDRT 180
  181 EIDLVLKSDV ASLDDFTPSG EWDIIALPGR RNENPDDSTY VDITYDFIIR RKPLFYTINL 240
  241 IIPCVLITSL AILVFYLPSD CGEKMTLCIS VLLALTVFLL LISKIVPPTS LDVPLVGKYL 300
  301 MFTMVLVTFS IVTSVCVLNV HHRSPTTHTM APWVKVVFLE KLPTLLFLQQ PRHRCARQRL 360
  361 RLRRRQRERE GAGALFFREG PAADPCTCFV NPASVQGLAG AFRAEPTAAG PGRSVGPCSC 420
  421 GLREAVDGVR FIADHMRSED DDQSVREDWK YVAMVIDRLF LWIFVFVCVF GTVGMFLQPL 480
  481 FQNYTATTFL HPDHSAPSSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle