Protein Overview: AXIN2_RAT

General Information:
Name(s) found:	AXIN2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|T08423 Axin homolog Axil - rat [NCBI NR] gi\|3080759\|gb\|AAC40089.1\| Axil; Axin like protein [Rattus norvegicus] [NCBI NR] gi\|13242243\|ref\|NP_077331.1\| axin2 [Rattus norvegicus] [NCBI NR] gi\|10719896\|sp\|O70240.1\|AXN2_RAT RecName: Full=Axin-2; AltName: Full=Axis inhibition protein 2; AltName: Full=Conductin; AltName: Full=Axin-like protein; Short=Axil [NCBI NR] Axin-2 OS=Rattus norvegicus GN=Axin2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-96509751 Axin 2 [hmr_yeast5_DM3-1_pombe.fasta] axin2; axin 2; axin-like [HMR_022704-rand.fasta] axin2 [Rattus norvegicus]gi\|10719896\|sp\|O70240\|AXN2_RAT Axin 2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil)gi\|7513917\|pir\|\|T08423 Axin homolog Axil - ratgi\|3080759\|gb\|AAC40089.1\| Axil; Axin like protein [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Axin-2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_024355) axin 2; axin2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] axin2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Axil; Axin like protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 AXIN 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Axin2 Axin-2 [rat-ipi-250309-contam.fasta] Axin-2 OS=Rattus norvegicus GN=Axin2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	838 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] cytoplasm [IEA] cellular_component [ND] intracellular [IEA]
Biological Process:	cell death [IDA] somitogenesis [UNKNOWN][IEA] multicellular organismal development [IEA] negative regulation of cell proliferation [UNKNOWN][IDA] intramembranous ossification [UNKNOWN][IEA] negative regulation of Wnt receptor signaling pathway [IDA] regulation of Wnt receptor signaling pathway [UNKNOWN] negative regulation of osteoblast differentiation [UNKNOWN][IEA]
Molecular Function:	protein kinase binding [IPI] protein binding [UNKNOWN] beta-catenin binding [IDA] signal transducer activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSAVLVTLL PDPSSSFRED APRPPVPGEE GETPPCQPSV GKVQSTKPMP VSSNARRNED  60
   61 GLGEPEGRAS PDSPLTRWTK SLHSLLGDQD GAYLFRTFLE REKCVDTLDF WFACNGFRQM 120
  121 NLKDTKTLRV AKAIYKRYIE NNSVVSKQLK PATKTYIRDG IKKQQIGSVM FDQAQTEIQA 180
  181 VMEENAYQVF LTSDIYLEYV RSGGENTAYM SNGGLGSLKV LCGYLPTLNE EEEWTCADLK 240
  241 CKLSPTVVGL SSKTLRATAS VRSTETAENG FRSFKRSEPV NPYHVGSGYV FAPATSANDS 300
  301 ELSSDALTDD SMSMTDSSVD GIPPYRMGSK KQLQREMHRS VKANGQVSLP HFPRTHRLPK 360
  361 EMTPVEPAAF AAELISRLEK LKLELESRHS LEERLQQIRE DEEKEGSEQA LSSRDGAPVQ 420
  421 HPLALLPSGS YEEDPQTILD DHLSRVLKTP GCQSPGVGRY SPRSRSPDHH HHHHQQCHAL 480
  481 LPTGGKLPPE AACPLLGGKS FLTKQTTKHV HHHYIHHHAV PKTKEEIEAE ATQRVRCLCP 540
  541 GGTDYYCYSK CKSHSKPPEP LPGEQFCGSR GGTLPKRNTK GTEPGLALPA REGGMSSAAG 600
  601 APQLPGEEGD RSQDVWQWML ESERQSKSKP HSTQSIRKSY PLESARAPPG ERVSRHHLLG 660
  661 ASGHPRSAAR AHPFTQDPAM PPLTPPNTLA QLEEACRRLA EVSKPQKQRC CVASQQRDRN 720
  721 HPATGQAGPT SFSNPSLASE DHKEPKRLAS VHALQASELI VTYFFCGEEI PYRRMLKAQS 780
  781 LTLGHFKEQL SKKGNYRYYF KKASDEFACG AVFEEIWDDE TVLPMYEGRI LGKVERID

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: AXIN2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: