Protein Overview: PCSK4_RAT

General Information:
Name(s) found:	PCSK4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|51316131\|sp\|Q78EH2.1\|PCSK4_RAT RecName: Full=Proprotein convertase subtilisin/kexin type 4; Short=PC4; AltName: Full=Neuroendocrine convertase 3; Short=NEC 3; AltName: Full=Prohormone convertase 3; AltName: Full=KEX2-like endoprotease 3; Flags: Precurs [NCBI NR] gi\|294609\|gb\|AAA41815.1\| proprotein convertase 4 [Rattus norvegicus] [NCBI NR] Proprotein convertase subtilisin/kexin type 4 OS=Rattus norvegicus GN=Pcsk4 PE=2 SV=1 [Swiss-Prot] (Q78EH2) Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3) [Swiss-Prot] Ensembl_locations(Chr-bp):7-3929798 Neuroendocrine convertase 3-B [hmr_yeast5_DM3-1_pombe.fasta] proprotein convertase 4 [Rattus norvegicus]gi\|2118124\|pir\|\|I77530 proprotein convertase 4 (EC 3.4.21.-) precursor, membrane-bound splice form - black ratgi\|51316131\|sp\|Q78EH2\|PCK4_RAT Proprotein convertase subtilisin/kexin type 4 precursor (PC4) (Neuroe [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Proprotein convertase subtilisin/kexin type 4 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Proprotein convertase subtilisin/kexin type 4 precursor (PC4) (Neuroendocrine convertase 3) (NEC 3) (Prohormone convertase 3) (KEX2-like endoprotease 3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] proprotein convertase 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 4 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Pcsk4 Isoform 1 of Proprotein convertase subtilisin/kexin type 4 [rat-ipi-250309-contam.fasta] Isoform 1 of Proprotein convertase subtilisin/kexin type 4 OS=Rattus norvegicus GN=Pcsk4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	678 amino acids
Gene Ontology:
Cellular Component:	acrosomal membrane [UNKNOWN]
Biological Process:	binding of sperm to zona pellucida [UNKNOWN] sperm capacitation [UNKNOWN] acrosome reaction [UNKNOWN] proteolysis [IEA] fertilization [UNKNOWN]
Molecular Function:	serine-type endopeptidase activity [IEA] peptidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPSQTALWL GLVLSLALLA VGWASARPPI YVSSWAVRVT KGYQEAERLA RKFGFVNLGQ  60
   61 IFPDDQYFHL RHRGVAQQSL TPHWGHRLRL KKEPKVRWFE QQTLRRRVKR SLVVPTDPWF 120
  121 SKQWYMNKEI EQDLNILKVW NQGLTGRGVV VSILDDGIEK DHPDLWANYD PLASYDFNDY 180
  181 DPDPQPRYTP NDENRHGTRC AGEVSATANN GFCGAGVAFN ARIGGVRMLD GAITDIVEAQ 240
  241 SLSLQPQHIH IYSASWGPED DGRTVDGPGL LTQEAFRRGV TKGRQGLGTL FIWASGNGGL 300
  301 HYDNCNCDGY TNSIHTLSVG STTRQGRVPW YSEACASTFT TTFSSGVVTD PQIVTTDLHH 360
  361 QCTDKHTGTS ASAPLAAGMI ALALEANPLL TWRDLQHLVV RASRPAQLQA EDWRINGVGR 420
  421 QVSHHYGYGL LDAGLLVDLA RVWLPTKPQK KCTIRVVHTP TPILPRMLVP KNVTVCCDGS 480
  481 RRRLIRSLEH VQVQLSLSYS RRGDLEIFLT SPMGTRSTLV AIRPLDISGQ GYNNWIFMST 540
  541 HYWDEDPQGL WTLGLENKGY YYNTGTLYYC TLLLYGTAED MTARPQTPQE SHCPLSIVAE 600
  601 LCLISSKQWW WLYSHTQQPV TKGQDSCHPP TTPARQLDQR LHCLFPAPHA GSASEPLQGL 660
  661 SPLAAILAIS LGPWCCPC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PCSK4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: