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Protein Overview: TEP1_RAT

General Information:
Name(s) found: TEP1_RAT [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • Telomerase protein component 1 OS=Rattus norvegicus GN=Tep1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 2629 amino acids

    Gene Ontology:
    Cellular Component: chromosome, telomeric region [IEA]
    nucleus [IEA]
    soluble fraction [UNKNOWN][IEA]
    ribonucleoprotein complex [IDA]
    cytoplasm [UNKNOWN][IEA]
    nuclear matrix [UNKNOWN][IEA]
    chromosome [IEA]
    telomerase holoenzyme complex [UNKNOWN][IEA]
    Biological Process: [NOT]telomere maintenance via telomerase [UNKNOWN]
    telomere maintenance via recombination [UNKNOWN][IEA]
    Molecular Function: nucleotide binding [IEA]
    telomerase activity [UNKNOWN][IEA]
    ATP binding [IEA]
    RNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKLCGYVPV HPDILSLKNR CLTMLSDIQP LEKIHGQRSV NPDILSLENR CLTLLPDLQP  60
   61 MEKIHGQRSV HPDILSSENR CLTLLPDLQS LEKLCGHMSS HPDVLSLENR CLATLPTVKR 120
  121 TVSSGPLLQC LHRSHTAQAD LRDPNFRNCL FPEPPTIEAP CFLKELDLPT GPRALKSMSA 180
  181 TARVQEVALG QRCVSEGKEL QEEKESAEVP MPLYSLSLGG EEEEVVGAPV LKLTSGDSDS 240
  241 HPETTDQILQ EKKMALLTLL CSAMASSVNV KDASDPTRAS IHEVCSALAP LEPEFILKAS 300
  301 LYARQQLNLR DIANIVLAVA ALLPACRPHV RRYYSAIVHL PSDWIQVAEF YQSLAEGDEK 360
  361 KLVPLPACLR AAMTDKFAQF DEYQLAKYNP RKHRSKTRSR QPPRPQRTKP PFSESGKCFP 420
  421 KSVWPLKNEQ ISFEAAYNAV SEKKRLPRFT LKKLVEQLHI HEPAQHVQAL LGYRYPSTLE 480
  481 LFSRSHLPGP WDSSRAGQRM KLQRPETWER ELSLRGNRAS VWEELIDNGK LPFMAMLRNL 540
  541 CNLLRTGISA HHHELVLQRL QHEKSVIHSR QFPFRFLNAH DSLDRLEAQL RSKASPFPSN 600
  601 TTLMKRIMIR NSKKIKRPAN PRYLCTLTQR QLRAAMAIPV MYEHLKREKL RLHKARQWTC 660
  661 DLELLERYRQ ALETAVNISV KHNLPPLPGR TLLVYLTDAN ANRLCPKSHL QGPPLNYVLL 720
  721 LIGMMMARAE QTTVWLCGTG TVKTPVLTAD EGILKTAIKL QAQVQELEEN DEWPLETFEK 780
  781 YLLSLAVRRT PIDRVILFGQ RMDTELLNVA KQIIWQHVNS KCLFVSVLLR KMQYMSPNLN 840
  841 PNDVTLSGCT DGILKFIAEH GASRLLEHVG QLDKIFKIPP PPGKTKVSPL RPLEENNPGP 900
  901 FVPISQHGWR NIRLFISSTF RDMHGERDLL MRSVLPALQA RAFPHRISLH AIDLRWGITE 960
  961 EETRRNRQLE VCLGEVENSQ LFVGILGSRY GYTPPSYDLP DHPHFHWTQR YPSGRSVTEM1020
 1021 EVMQFLNRGQ RSEPSDQALI YFRDPGFLSS VPDVWKPDFI SESEEAAHRV SELKRFLQEQ1080
 1081 KEVTCRRYSC EWGGVAAGRP YTGGLEEFGQ LVLQDVWSVI QKRYLQPGAQ LEQPGSISEE1140
 1141 DLIQASFQQL KSPPSPARPR LLQDTVQQLM LPHGRLSLVI GQAGQGKTAF LASLVSALKV1200
 1201 PDQPNVAPFV FFHFSAARPD QCLAFNLLRR LCTHLHQKLG EPSALPSTYR GLVWELQQKL1260
 1261 LLKSAQWLQP GQTLVLIIDG ADKLVDHNGQ LISDWIPKSL PRRVHLVLSV SSDSGLGETL1320
 1321 QQSQSAYVVA LGSLVPSSRA QLVREELALY GKRLEESPFN NQMRLLLAKQ GSSLPLYLHL1380
 1381 VTDYLRLFTL YEQVSERLRT LPATLPLLLQ HILSTLEQEH GHNVLPQALT ALEVTHSGLT1440
 1441 VDQLHAVLST WLTLPKETKS WEEAVAASHS GNLYPLAPFA YLVQSLRSLL GEGPVERPGA1500
 1501 RLCLSDGPLR TAVKRRYGKR LGLEKTAHVL IAAHLWKMCD PDASGTFRSC PPEALKDLPY1560
 1561 HLLQSGNHGL LAKFLTNLHV VAAYLEVGLV PDLLEAYELY ASSKPEVNQK LPEADVAVFH1620
 1621 NFLKQQASLL TQYPLLLLQQ AASQPEESPV CCQAPLLTQR WHNQCILKWI NKPQTLKGQQ1680
 1681 SLSLPISSSP TAVAFSPNGQ RAAVGTAGGT IYLLNLRTWQ EEKALVSGCD GISSFAFLSD1740
 1741 TALFLTTFDG LLELWDLQHG CWVFQTKAHQ YQITGCCLSP DRRLLATVCL GGYVKLWDTV1800
 1801 QGQLAFQYTH PKSLNCITFH PEGQVVATGN WSGIVTFFQA DGLKVTKELG GPGPSVRTLA1860
 1861 FSAPGKVVAL GRIDGTVELW AWQEGTRLAA FPAQCGGVST VLFLHAGGRF LTAGEDGKAQ1920
 1921 LWSGFLGRPR GCLGSLYLSP ALSVALNPDG DQVAVGYRGD GIKIYRISSG PQEAQCQELN1980
 1981 VAVSALVWLS PSVLVSGAED GSLHGWMLRR NSLQSLWLSS VCQKPVLGLA ASQEFLASAS2040
 2041 EDFTVRLWPR QLLTQPHAVE ELPCAAELRG HEGPVCCCSF SPDGRILATA GRDRNLLCWD2100
 2101 VKVAQAPLLI HTFSSCHRDW ITGCTWTKDN ILISCSSDGS VGLWNPEAGQ QLGQFPGHQS2160
 2161 AVSAVVAVEE HIVSVSRDGT LKVWDRQGVE LTSIPAHSGP ISQCAAALEP RPAGQPGSEL2220
 2221 MVVTVGLDGA TKLWHPLLVC QIHTLQGHSG PVTAAAASEA SGLLLTSDNS SVRLWQIPKE2280
 2281 ADDTCKPRSS AVITAVAWAP DGSLVVSGNE AGELTLWQKA QAVATARAPG RVSDLIWCSA2340
 2341 NAFFVLSANE NVSEWQVELR KGSTCTNFRL YLKRVLQEDL GVLTGMALAP DGQSLILMKE2400
 2401 DVELLQMKPG STPSSICRRY AVHSSILCTS KDYGLFYLQQ GNSGSLSILE QEESGKFEKT2460
 2461 LDFNLNLNNP NGSPVSITQA EPESGSSLLC ATSDGMLWNL SECTPEGEWV VDNIWQKKSR2520
 2521 NPKSRTPGTD SSPGLFCMDS WVEPTHLKAR QCKKIHLGSV TALHVLPGLL VTASEDRDVK2580
 2581 LWERPSMQLL GLFRCEGPVS CLEPWMEPSS PLQLAVGDAQ GNLYFLSWE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle