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Protein Overview: CGL_RAT

General Information:
Name(s) found: CGL_RAT [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Cystathionine gamma-lyase OS=Rattus norvegicus GN=Cth PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 398 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    cellular_component [ND]
    Biological Process: hydrogen sulfide biosynthetic process [UNKNOWN][ISS]
    protein homotetramerization [UNKNOWN][IEA]
    protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine [UNKNOWN][ISS]
    negative regulation of cell growth [IMP]
    glutathione metabolic process [IMP]
    negative regulation of cell proliferation [IMP]
    cysteine biosynthetic process [UNKNOWN][IDA][ISS]
    cellular amino acid metabolic process [IEA]
    cellular amino acid biosynthetic process [IEA]
    transsulfuration [TAS]
    homocysteine metabolic process [IDA]
    Molecular Function: pyridoxal phosphate binding [UNKNOWN][IEA][ISS][TAS]
    catalytic activity [IEA]
    lyase activity [IEA]
    cystathionine beta-lyase activity [IDA]
    cystathionine gamma-lyase activity [UNKNOWN][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKDASSSGF LPSFQHFATQ AIHVGPEPEQ WSSRAVVLPI SLATTFKQDS PGQSSGFVYS  60
   61 RSGNPTRNCL EKAVAALDGA KHCLTFARGL AATTTITHLL KAGDEVICMD EVYGGTNRYF 120
  121 RRVASEFGLK ISFVDCSKTK LLEAAITPQT KLVWIETPTN PTLKLADIKA CAQIVHKHKD 180
  181 IILVVDNTFM SAYFQRPLAL GADICMCSAT KYMNGHSDVV MGLVSVTSDD LNERLRFLQN 240
  241 SLGAVPSPFD CYLCCRGLKT LQIRMEKHFR NGMAVARFLE SNPRVEKVIY PGLPSHPQHE 300
  301 LAKRQCTGCP GMVSFYIKGT LQHAQVFLKN IKLFALAESL GGYESLAELP AIMTHASVPE 360
  361 KDRATLGISD TLIRLSVGLE DEKDLLEDLG QALKAAHP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.68

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle