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Protein Overview: FOLD_PHOLL

General Information:
Name(s) found: FOLD_PHOLL [Swiss-Prot]
Description(s) found:
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  • gi|81418221|sp|Q7MZH1.1|FOLD_PHOLL RecName: Full=Bifunctional protein folD; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase [NCBI NR]
  • Bifunctional protein folD OS=Photorhabdus luminescens subsp. laumondii GN=folD PE=3 SV=1 [Swiss-Prot]
  • Bifunctional protein FolD OS=Photorhabdus luminescens subsp. laumondii (strain TT01) GN=folD PE=3 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Photorhabdus luminescens subsp. laumondii
    Length: 291 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAKIIDGKT IAQTIRSEVA VRVQQRVAAG RRAPGLAVVL VGENPASQIY VASKRRACEE  60
   61 VGFVSRSYDL PDTTSEAELL NLIDQLNNDS DIDGILVQLP LPAGIDNVKV LERIQPDKDV 120
  121 DGFHPYNIGR LCQRAPKLRP CTPRGIATLL ERCGINTYGL NAVIIGASNI VGRPMSLELL 180
  181 LAGCTTTVTH RFTKDLRHHV EQADLLIVAV GKPNFIPGEW IKPGAIVIDV GINRLEDGKV 240
  241 IGDVDFETAS ERASWISPVP GGVGPMTVAT LIQNTLQACE EYHDVERIEG C

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..291] PSI-BLAST 118.0 Methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Tetrahydrofolate dehydrogenase/cyclohydrolase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity
    		•  3.54983447672782 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.66605122152932 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  2.43636049081724 bayes_pls_golite062009
  • binding
    		•  2.29686796649236 bayes_pls_golite062009
  • catalytic activity
    		•  2.0643953589843 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.95832530533882 bayes_pls_golite062009
  • methenyltetrahydrofolate cyclohydrolase activity
    		•  1.95551536198286 bayes_pls_golite062009
  • DNA binding
    		•  1.70073234884672 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.54527841865655 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.47211855405194 bayes_pls_golite062009
  • malic enzyme activity
    		•  1.39067036188188 bayes_pls_golite062009
  • transcription factor activity
    		•  0.9895904275677 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
    		•  0.66392365734856 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  0.129148522173579 bayes_pls_golite062009
  • ligase activity
    		•  0.0191278372003161 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle