Protein Overview: ITA1_RAT

General Information:
Name(s) found:	ITA1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|56494\|emb\|CAA36384.1\| unnamed protein product [Rattus norvegicus] [NCBI NR] gi\|149059385\|gb\|EDM10392.1\| integrin alpha 1, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|13591884\|ref\|NP_112256.1\| integrin alpha 1 [Rattus norvegicus] [NCBI NR] gi\|124941\|sp\|P18614.1\|ITA1_RAT RecName: Full=Integrin alpha-1; AltName: Full=Laminin and collagen receptor; AltName: Full=VLA-1; AltName: Full=CD49 antigen-like family member A; AltName: CD_antigen=CD49a; Flags: Precursor [NCBI NR] pir\|\|A35854 integrin alpha-1 chain precursor - rat [NCBI NR] Integrin alpha-1 OS=Rattus norvegicus GN=Itga1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):2-42751733;2-42751733 Integrin alpha-1 precursor [hmr_yeast5_DM3-1_pombe.fasta] integrin alpha 1; integrin, alpha 1 [HMR_022704-rand.fasta] integrin alpha 1 [Rattus norvegicus]gi\|56494\|emb\|CAA36384.1\| unnamed protein product [Rattus norvegicus]gi\|111872\|pir\|\|A35854 integrin alpha-1 chain precursor - ratgi\|124941\|sp\|P18614\|ITA1_RAT Integrin alpha-1 precursor (Laminin and collagen receptor) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Integrin alpha-1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_030994) integrin, alpha 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Integrin alpha-1 precursor (Laminin and collagen receptor) (VLA-1) (CD49 antigen-like family member A) (CD49a antigen) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] integrin alpha 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] integrin alpha 1, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 INTEGRIN ALPHA-1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Integrin alpha-1 precursor (Laminin and collagen receptor) (VLA-1) (CD49a antigen) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Itga1 Integrin alpha-1 [rat-ipi-250309-contam.fasta] integrin, alpha 1 precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Integrin alpha-1 OS=Rattus norvegicus GN=Itga1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1180 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] acrosomal vesicle [IDA] membrane [IEA] membrane raft [IDA] external side of plasma membrane [UNKNOWN][IDA] integral to membrane [IEA] perikaryon [IDA] integrin complex [IMP] neuron projection [IDA]
Biological Process:	activation of MAPK activity [IMP] integrin-mediated signaling pathway [IEA] cellular extravasation [UNKNOWN][IEA] muscle contraction [UNKNOWN] neuron projection morphogenesis [IMP] neutrophil chemotaxis [UNKNOWN][IEA] cell adhesion [UNKNOWN][IEA] vasodilation [IMP] positive regulation of neuron apoptosis [IMP] cell chemotaxis [IMP]
Molecular Function:	protein binding [UNKNOWN][IPI] collagen binding [IMP] protein heterodimerization activity [IMP] integrin binding [IMP] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPRRPASLE VTVACIWLLT VILGFCVSFN VDVKNSMSFS GPVEDMFGYT VQQYENEEGK  60
   61 WVLIGSPLVG QPKARTGDVY KCPVGRERAM PCVKLDLPVN TSIPNVTEIK ENMTFGSTLV 120
  121 TNPNGGFLAC GPLYAYRCGH LHYTTGICSD VSPTFQVVNS FAPVQECSTQ LDIVIVLDGS 180
  181 NSIYPWESVI AFLNDLLKRM DIGPKQTQVG IVQYGENVTH EFNLNKYSST EEVLVAANKI 240
  241 GRQGGLQTMT ALGIDTARKE AFTEARGARR GVKKVMVIVT DGESHDNYRL KQVIQDCEDE 300
  301 NIQRFSIAIL GHYNRGNLST EKFVEEIKSI ASEPTEKHFF NVSDELALVT IVKALGERIF 360
  361 ALEATADQSA ASFEMEMSQT GFSAHYSQDW VMLGAVGAYD WNGTVVMQKA NQMVIPHNTT 420
  421 FQTEPAKMNE PLASYLGYTV NSATIPGDVL YIAGQPRYNH TGQVVIYKME DGNINILQTL 480
  481 GGEQIGSYFG SVLTTIDIDK DSYTDLLLVG APMYMGTEKE EQGKVYVYAV NQTRFEYQMS 540
  541 LEPIRQTCCS SLKDNSCTKE NKNEPCGARF GTAIAAVKDL NVDGFNDVVI GAPLEDDHAG 600
  601 AVYIYHGSGK TIREAYAQRI PSGGDGKTLK FFGQSIHGEM DLNGDGLTDV TIGGLGGAAL 660
  661 FWARDVAVVK VTMNFEPNKV NIQKKNCRVE GKETVCINAT MCFHVKLKSK EDSIYEADLQ 720
  721 YRVTLDSLRQ ISRSFFSGTQ ERKIQRNITV RESECIRHSF YMLDKHDFQD SVRVTLDFNL 780
  781 TDPENGPVLD DALPNSVHEH IPFAKDCGNK ERCISDLTLN VSTTEKSLLI VKSQHDKFNV 840
  841 SLTVKNKGDS AYNTRTVVQH SPNLIFSGIE EIQKDSCESN QNITCRVGYP FLRAGETVTF 900
  901 KIIFQFNTSH LSENAIIHLS ATSDSEEPLE SLNDNEVNIS IPVKYEVGLQ FYSSASEHHI 960
  961 SVAANETIPE FINSTEDIGN EINVFYTIRK RGHFPMPELQ LSISFPNLTA DGYPVLYPIG1020
 1021 WSSSDNVNCR PRSLEDPFGI NSGKKMTISK SEVLKRGTIQ DCSSTCGVAT ITCSLLPSDL1080
 1081 SQVNVSLLLW KPTFIRAHFS SLNLTLRGEL KSENSSLTLS SSNRKRELAI QISKDGLPGR1140
 1141 VPLWVILLSA FAGLLLLMLL ILALWKIGFF KRPLKKKMEK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ITA1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: