Protein Overview: EAA1_RAT

General Information:
Name(s) found:	EAA1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|56269\|emb\|CAA45276.1\| glutamate/aspartate transporter [Rattus norvegicus] [NCBI NR] pir\|\|S26609 glutamate/aspartate transport protein - rat [NCBI NR] gi\|232176\|sp\|P24942.2\|EAA1_RAT RecName: Full=Excitatory amino acid transporter 1; AltName: Full=Sodium-dependent glutamate/aspartate transporter 1; Short=GLAST-1; AltName: Full=Glial glutamate transporter; AltName: Full=Solute carrier family 1 member 3 [NCBI NR] Excitatory amino acid transporter 1 OS=Rattus norvegicus GN=Slc1a3 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):2-51813726;2-51813726;2-51813726;2-51813726 Splice isoform GLAST-1 of P24942 [hmr_yeast5_DM3-1_pombe.fasta] glutamate/aspartate transporter [Rattus norvegicus]gi\|232176\|sp\|P24942\|EAA1_RAT Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (Glial glutamate transporter) (GLAST) (GLAST-1)gi\|285094\|pir\|\|S26609 glutamate/aspar [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform GLAST-1 of Excitatory amino acid transporter 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Glial glutamate transporter) (Solute carrier family 1 member 3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamate/aspartate transporter [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF EXCITATORY AMINO ACID TRANSPORTER 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Excitatory amino acid transporter 1 (Sodium-dependent glutamate/aspartate transporter 1) (Glial glutamate transporter) (GLAST) (GLAST-1) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Slc1a3 Isoform GLAST-1 of Excitatory amino acid transporter 1 [rat-ipi-250309-contam.fasta] Isoform GLAST-1 of Excitatory amino acid transporter 1 OS=Rattus norvegicus GN=Slc1a3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	543 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] dendritic spine [IDA] integral to membrane [IEA] neuronal cell body [UNKNOWN][IEA] synapse [IDA] basolateral plasma membrane [IDA] cell projection [UNKNOWN] neuron projection [IDA] mitochondrial inner membrane [IDA] plasma membrane [UNKNOWN][IDA] cell surface [UNKNOWN][IEA] fibril [UNKNOWN][IEA]
Biological Process:	L-glutamate import [UNKNOWN][IEA] positive regulation of synaptic transmission [UNKNOWN][IEA] response to wounding [UNKNOWN][IEA] response to antibiotic [UNKNOWN][IEA] cranial nerve development [UNKNOWN][IEA] cell morphogenesis involved in neuron differentiation [UNKNOWN][IEA] response to light stimulus [UNKNOWN][IEA] gamma-aminobutyric acid biosynthetic process [UNKNOWN][IEA] dicarboxylic acid transport [IEA] sensory perception of sound [UNKNOWN][IEA] neurotransmitter transport [TAS] glutamate metabolic process [UNKNOWN] glutamate biosynthetic process [UNKNOWN][IEA] malate-aspartate shuttle [IDA] response to drug [UNKNOWN][IEA] auditory behavior [UNKNOWN][IEA] L-glutamate transport [UNKNOWN][IDA][IMP] response to inorganic substance [IDA] D-aspartate import [UNKNOWN][IEA] neuromuscular process controlling balance [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN][IEA] sodium:dicarboxylate symporter activity [IEA] symporter activity [IEA] glutamate binding [UNKNOWN][IEA] amino acid binding [UNKNOWN] high-affinity glutamate transmembrane transporter activity [UNKNOWN][IMP] L-glutamate transmembrane transporter activity [IDA][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKSNGEEPR MGSRMERFQQ GVRKRTLLAK KKVQNITKED VKSYLFRNAF VLLTVSAVIV  60
   61 GTILGFALRP YKMSYREVKY FSFPGELLMR MLQMLVLPLI ISSLVTGMAA LDSKASGKMG 120
  121 MRAVVYYMTT TIIAVVIGII IVIIIHPGKG TKENMYREGK IVQVTAADAF LDLIRNMFPP 180
  181 NLVEACFKQF KTSYEKRSFK VPIQANETLL GAVINNVSEA METLTRIREE MVPVPGSVNG 240
  241 VNALGLVVFS MCFGFVIGNM KEQGQALREF FDSLNEAIMR LVAVIMWYAP LGILFLIAGK 300
  301 ILEMEDMGVI GGQLAMYTVT VIVGLLIHAV IVLPLLYFLV TRKNPWVFIG GLLQALITAL 360
  361 GTSSSSATLP ITFKCLEENN GVDKRITRFV LPVGATINMD GTALYEALAA IFIAQVNNFD 420
  421 LNFGQIITIS ITATAASIGA AGIPQAGLVT MVIVLTSVGL PTDDITLIIA VDWFLDRLRT 480
  481 TTNVLGDSLG AGIVEHLSRH ELKNRDVEMG NSVIEENEMK KPYQLIAQDN EPEKPVADSE 540
  541 TKM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: EAA1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: