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Protein Overview: SLIB_RAT

General Information:
Name(s) found: SLIB_RAT [Swiss-Prot]
Description(s) found:
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  • gi|498585|gb|AAC52184.1| growth hormone-releasing hormone [NCBI NR]
  • gi|224441|prf||1104311A somatoliberin [NCBI NR]
  • gi|204312|gb|AAA41220.1| growth hormone-releasing hormone [NCBI NR]
  • gi|149043115|gb|EDL96689.1| growth hormone releasing hormone, isoform CRA_b [Rattus norvegicus] [NCBI NR]
  • gi|149043112|gb|EDL96686.1| growth hormone releasing hormone, isoform CRA_b [Rattus norvegicus] [NCBI NR]
  • gi|13928782|ref|NP_113765.1| growth hormone releasing hormone [Rattus norvegicus] [NCBI NR]
  • gi|134524|sp|P09916.2|SLIB_RAT RecName: Full=Somatoliberin; AltName: Full=Growth hormone-releasing factor; Short=GRF; AltName: Full=Growth hormone-releasing hormone; Short=GHRH; Flags: Precursor [NCBI NR]
  • gi|1279657|emb|CAA26194.1| growth hormone-releasing factor [Rattus norvegicus] [NCBI NR]
  • pir||A32731 somatoliberin precursor - rat [NCBI NR]
  • Somatoliberin OS=Rattus norvegicus GN=Ghrh PE=1 SV=2 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):3-140651435;3-140651435 Somatoliberin precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • growth hormone releasing hormone [HMR_022704-rand.fasta]
  • growth hormone releasing hormone [Rattus norvegicus]gi|1279657|emb|CAA26194.1| growth hormone-releasing factor [Rattus norvegicus]gi|498585|gb|AAC52184.1| growth hormone-releasing hormonegi|112315|pir||A32731 somatoliberin precursor - ratgi|134524|sp| [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Somatoliberin precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_031577) growth hormone releasing hormone precursor [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Somatoliberin precursor (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • growth hormone releasing hormone [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • growth hormone releasing hormone, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • growth hormone-releasing factor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • growth hormone-releasing hormone [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • somatoliberin [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 SOMATOLIBERIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Ghrh Somatoliberin [rat-ipi-250309-contam.fasta]
  • growth hormone releasing hormone precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Somatoliberin OS=Rattus norvegicus GN=Ghrh [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 104 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN][IDA]
    terminal button [UNKNOWN]
    extracellular region [IEA]
    perikaryon [IDA]
    cellular_component [ND]
    neuron projection [IDA]
    axon terminus [IDA]
    Biological Process: response to food [UNKNOWN]
    circadian sleep/wake cycle, non-REM sleep [IDA]
    positive regulation of growth hormone secretion [UNKNOWN]
    positive regulation of cell proliferation [UNKNOWN]
    adenohypophysis development [UNKNOWN][TAS]
    positive regulation of cAMP biosynthetic process [UNKNOWN]
    positive regulation of transcription [IDA]
    positive regulation of hormone secretion [UNKNOWN]
    G-protein signaling, coupled to cAMP nucleotide second messenger [IDA]
    activation of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN][IDA]
    [NOT]positive regulation of circadian sleep/wake cycle, REM sleep [UNKNOWN]
    positive regulation of multicellular organism growth [UNKNOWN]
    elevation of cytosolic calcium ion concentration [IDA]
    positive regulation of cAMP metabolic process [IDA]
    growth hormone secretion [UNKNOWN][IDA][IMP][TAS]
    cAMP-mediated signaling [UNKNOWN]
    Molecular Function: growth hormone-releasing hormone activity [UNKNOWN][IDA]
    growth hormone-releasing hormone receptor binding [UNKNOWN][IC]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLWVFFVLL TLTSGSHCSL PPSPPFRVRR HADAIFTSSY RRILGQLYAR KLLHEIMNRQ  60
   61 QGERNQEQRS RFNRHLDRVW AEDKQMALES ILQGFPRMKL SAEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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