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Protein Overview: TPH1_RAT

General Information:
Name(s) found: TPH1_RAT [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • Tryptophan 5-hydroxylase 1 OS=Rattus norvegicus GN=Tph1 PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 444 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [TAS]
    cytosol [UNKNOWN]
    neuron projection [IDA]
    Biological Process: aromatic amino acid family metabolic process [IEA]
    mammary gland alveolus development [UNKNOWN][IEA]
    oxidation reduction [IEA]
    serotonin biosynthetic process from tryptophan [TAS]
    response to stress [IEP]
    Molecular Function: iron ion binding [IEA]
    metal ion binding [IEA]
    amino acid binding [IEA]
    tryptophan 5-monooxygenase activity [UNKNOWN][IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIEDNKENKD HSSERGRVTL IFSLKNEVGG LIKALKIFQE NHVNLLHIES RKSKRRNSEF  60
   61 EIFVDCDINR EQLNDIFPLL KSHTTVLSVD SPDQLPEKED VMETVPWFPK KISDLDFCAN 120
  121 RVLLYGSELD ADHPGFKDNV YRRRRKYFAE LAMNYKHGDP IPKIEFTEEE IKTWGTIFRE 180
  181 LNKLYPTHAC REYLRNLPLL SKYCGYREDN VPQLEDVSNF LKERTGFSIR PVAGYLSPRD 240
  241 FLSGLAFRVF HCTQYVRHSS DPLYTPEPDT CHELLGHVPL LAEPSFAQFS QEIGLASLGA 300
  301 SEETVQKLAT CYFFTVEFGL CKQDGQLRVF GAGLLSSISE LRHALSGHAK VKPFDPKVAC 360
  361 KQECLITSFQ DVYFVSESFE DAKEKMREFA KTVKRPFGVK YNPYTQSIQV LRDSKSITSA 420
  421 MNELRHDLDV VNDALARVSR WPSV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle