Protein Overview: HNF1B_RAT

General Information:
Name(s) found:	HNF1B_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6981640\|ref\|NP_037235.1\| transcription factor 2, hepatic [Rattus norvegicus] [NCBI NR] gi\|57478\|emb\|CAA39886.1\| variant hepatic nuclear factor 1 (vHNF1) [Rattus norvegicus] [NCBI NR] gi\|51859462\|gb\|AAH81826.1\| HNF1 homeobox B [Rattus norvegicus] [NCBI NR] gi\|123440\|sp\|P23899.1\|HNF1B_RAT RecName: Full=Hepatocyte nuclear factor 1-beta; Short=HNF-1-beta; Short=HNF-1B; AltName: Full=Transcription factor 2; Short=TCF-2; AltName: Full=Variant hepatic nuclear factor 1; Short=vHNF1 [NCBI NR] pir\|\|S15342 transcription factor HNF-1B - rat [NCBI NR] (P23899) Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) [Swiss-Prot] Hepatocyte nuclear factor 1-beta OS=Rattus norvegicus GN=Hnf1b PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-70189173 Splice isoform VHNF1-A of P23899 [hmr_yeast5_DM3-1_pombe.fasta] transcription factor 2, hepatic; Transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor; variant hepatic nuclear factor; Transcription factor 2 hepatic; LF-B3; variant hepatic nuclear factor [HMR_022704-rand.fasta] transcription factor 2, hepatic [Rattus norvegicus]gi\|51859462\|gb\|AAH81826.1\| Transcription factor 2, hepatic [Rattus norvegicus]gi\|57478\|emb\|CAA39886.1\| variant hepatic nuclear factor 1 (vHNF1) [Rattus norvegicus]gi\|123440\|sp\|P23899\|HNFB_RAT Hepatocyt [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform VHNF1-A of Hepatocyte nuclear factor 1-beta [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_013103) transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Hepatocyte nuclear factor 1-beta (HNF-1-beta) (HNF-1B) (Transcription factor 2) (TCF-2) (Variant hepatic nuclear factor 1) (vHNF1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] HNF1 homeobox B [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] transcription factor 2, hepatic [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] variant hepatic nuclear factor 1 (vHNF1) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF HEPATOCYTE NUCLEAR FACTOR 1-BETA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) [nr-271106-contam.fasta] Transcription factor 2 [Rattus norvegicus] [nr-271106-contam.fasta] Hepatocyte nuclear factor 1-beta OS=Rattus norvegicus GN=Hnf1b PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta] Isoform of P23899, Hepatocyte nuclear factor 1-beta OS=Rattus norvegicus GN=Hnf1b PE=1 SV=3 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	557 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA][TAS] transcription factor complex [UNKNOWN] [NOT]nucleolus [UNKNOWN]
Biological Process:	insulin secretion [UNKNOWN] endoderm development [UNKNOWN] anterior/posterior pattern formation [UNKNOWN] embryonic gut morphogenesis [UNKNOWN] epithelium development [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA][IMP] hepatoblast differentiation [UNKNOWN] response to glucose stimulus [UNKNOWN] circadian regulation of gene expression [IDA] epithelial cell proliferation [UNKNOWN] kidney development [UNKNOWN] hindbrain development [UNKNOWN] positive regulation of transcription, DNA-dependent [UNKNOWN] hepatocyte differentiation [IEP] liver development [UNKNOWN] inner cell mass cell differentiation [UNKNOWN] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] response to protein stimulus [IEP] endocrine pancreas development [UNKNOWN] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] genitalia development [UNKNOWN] protein-DNA complex assembly [IMP] response to carbohydrate stimulus [IEP] response to organic cyclic substance [IEP] regulation of endodermal cell fate specification [UNKNOWN] response to drug [IEP] negative regulation of apoptosis [UNKNOWN] endodermal cell fate specification [UNKNOWN] cellular response to protein stimulus [UNKNOWN]
Molecular Function:	DNA binding [UNKNOWN][TAS] transcription factor activity [UNKNOWN][TAS] protein binding [UNKNOWN] protein homodimerization activity [UNKNOWN][IDA] protein heterodimerization activity [UNKNOWN][IDA] sequence-specific DNA binding [IDA] promoter binding [IDA] transcription activator activity [IDA] protein complex binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSKLTSLQQ ELLSALLSSG VTKEVLIQAL EELLPSPNFG VKLETLPLSP GSGADLDTKP  60
   61 VFHTLTNGHA KGRLSGDEGS EDGDDYDTPP ILKELQALNT EEAAEQRAEV DRMLSEDPWR 120
  121 AAKMIKGYMQ QHNIPQREVV DVTGLNQSHL SQHLNKGTPM KTQKRAALYT WYVRKQREIL 180
  181 RQFNQTVQSS GNMTDKSSQD QLLFLFPEFS QQNQGPGQSE DACSEPTNKK MRRNRFKWGP 240
  241 ASQQILYQAY DRQKNPSKEE REALVEECNR AECLQRGVSP SKAHGLGSNL VTEVRVYNWF 300
  301 ANRRKEEAFR QKLAMDAYSS NQTHNLNPLL THGSPHHQPS SSPPNKLSGV RYSQPGNNEV 360
  361 TSSSTISHHG NSAMVTSQSV LQQVSPASLD PGHSLLSPDS KMISVSGGGL PPVSTLTNIH 420
  421 SLSHHNPQQS QNLIMTPLSG VMAIAQSLNT SQAQGVPVIN SVASSLAALQ PVQFSQQLHS 480
  481 PHQQPLMQQS PGSHMAQQPF MAAVTQLQNS HMYAHKQEPP QYSHTSRFPS AMVVTDTSSI 540
  541 NTLTSMSSSK QCPLQAW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: HNF1B_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: