Protein Overview: LSHR_RAT

General Information:
Name(s) found:	LSHR_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|A49744 lutropin-choriogonadotropin receptor precursor - rat [NCBI NR] gi\|6981160\|ref\|NP_037110.1\| luteinizing hormone/choriogonadotropin receptor [Rattus norvegicus] [NCBI NR] gi\|205203\|gb\|AAA41529.1\| luteinizing hormone receptor [NCBI NR] gi\|205179\|gb\|AAA41528.1\| choriogonadotropic hormone receptor [NCBI NR] gi\|149050444\|gb\|EDM02617.1\| luteinizing hormone/choriogonadotropin receptor, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|126486\|sp\|P16235.1\|LSHR_RAT RecName: Full=Lutropin-choriogonadotropic hormone receptor; AltName: Full=LH/CG-R; AltName: Full=LSH-R; AltName: Full=Luteinizing hormone receptor; Flags: Precursor [NCBI NR] Lutropin-choriogonadotropic hormone receptor OS=Rattus norvegicus GN=Lhcgr PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):9-118292685 Splice isoform 1 of P16235 [hmr_yeast5_DM3-1_pombe.fasta] luteinizing hormone/choriogonadotropin receptor; luteinizing hormone receptor [HMR_022704-rand.fasta] luteinizing hormone/choriogonadotropin receptor [Rattus norvegicus]gi\|252164\|gb\|AAB22680.1\| luteinizing hormone/chorionic gonadotropin receptor; LH/CG receptor [Rattus sp.]gi\|7441621\|pir\|\|A49744 lutropin-choriogonadotropin receptor precursor - ratgi\|21 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Lutropin-choriogonadotropic hormone receptor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012978) Luteinizing hormone/choriogonadotropin receptor; luteinizing hormone receptor [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] luteinizing hormone/choriogonadotropin receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Lutropin-choriogonadotropic hormone receptor precursor (LH/CG-R) (LSH-R) (Luteinizing hormone receptor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] luteinizing hormone/choriogonadotropin receptor, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] luteinizing hormone receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] choriogonadotropic hormone receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Lhcgr Isoform 1 of Lutropin-choriogonadotropic hormone receptor [rat-ipi-250309-contam.fasta] Isoform 1 of Lutropin-choriogonadotropic hormone receptor OS=Rattus norvegicus GN=Lhcgr [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	700 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] integral to plasma membrane [IDA] extracellular space [IDA] endosome [IDA] cytoplasm [IDA] intrinsic to external side of plasma membrane [IDA] endoplasmic reticulum [IDA] receptor complex [IDA] extracellular region [IEA] plasma membrane [IDA] lysosome [IDA]
Biological Process:	signal transduction [IEA] positive regulation of hormone biosynthetic process [IDA] G-protein signaling, coupled to cAMP nucleotide second messenger [IDA][IMP] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger [IDA] positive regulation of release of sequestered calcium ion into cytosol [IDA] protein targeting to lysosome [IMP] hormone-mediated signaling pathway [IDA] luteinizing hormone signaling pathway [IDA] positive regulation of calcium-mediated signaling [IDA] arachidonic acid secretion [IDA] response to drug [IEP] positive regulation of calcium ion transport into cytosol [IDA] regulation of steroid biosynthetic process [IEP] activation of adenylate cyclase activity [IDA]
Molecular Function:	luteinizing hormone receptor activity [IEA] peptide receptor activity, G-protein coupled [IDA] identical protein binding [IDA] protein binding [IDA] protein homodimerization activity [IDA] peptide hormone binding [IDA][IMP][IPI] receptor activity [IEA] ATPase binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRRVPALRQ LLVLAVLLLK PSQLQSRELS GSRCPEPCDC APDGALRCPG PRAGLARLSL  60
   61 TYLPVKVIPS QAFRGLNEVV KIEISQSDSL ERIEANAFDN LLNLSELLIQ NTKNLLYIEP 120
  121 GAFTNLPRLK YLSICNTGIR TLPDVTKISS SEFNFILEIC DNLHITTIPG NAFQGMNNES 180
  181 VTLKLYGNGF EEVQSHAFNG TTLISLELKE NIYLEKMHSG AFQGATGPSI LDISSTKLQA 240
  241 LPSHGLESIQ TLIALSSYSL KTLPSKEKFT SLLVATLTYP SHCCAFRNLP KKEQNFSFSI 300
  301 FENFSKQCES TVRKADNETL YSAIFEENEL SGWDYDYGFC SPKTLQCAPE PDAFNPCEDI 360
  361 MGYAFLRVLI WLINILAIFG NLTVLFVLLT SRYKLTVPRF LMCNLSFADF CMGLYLLLIA 420
  421 SVDSQTKGQY YNHAIDWQTG SGCGAAGFFT VFASELSVYT LTVITLERWH TITYAVQLDQ 480
  481 KLRLRHAIPI MLGGWLFSTL IATMPLVGIS NYMKVSICLP MDVESTLSQV YILSILILNV 540
  541 VAFVVICACY IRIYFAVQNP ELTAPNKDTK IAKKMAILIF TDFTCMAPIS FFAISAAFKV 600
  601 PLITVTNSKI LLVLFYPVNS CANPFLYAIF TKAFQRDFLL LLSRFGCCKR RAELYRRKEF 660
  661 SAYTSNCKNG FPGASKPSQA TLKLSTVHCQ QPIPPRALTH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: LSHR_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: