Protein Overview: TOPB1_MOUSE

General Information:
Name(s) found:	TOPB1_MOUSE [Swiss-Prot]
Description(s) found: Found 24 descriptions. SHOW ALL	DNA topoisomerase 2-binding protein 1 OS=Mus musculus GN=Topbp1 PE=1 SV=2 [Swiss-Prot]
Organism:	Mus musculus
Length:	1515 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] cytoskeleton [IEA] cytoplasm [IEA] intracellular [IEA] male germ cell nucleus [IDA] condensed nuclear chromosome [IDA]
Biological Process:	DNA repair [IEA] reciprocal meiotic recombination [UNKNOWN] response to DNA damage stimulus [IEA]
Molecular Function:	DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRNDQEPFL VKFLKSSDNS ECFFKALESI KELQSEDYLQ IITDEEALKI RENDKSLYIC  60
   61 DRFSGTVFDH LKQLGCRIVG PQVVTFCMRH QQCVPRAEHP VYNMIMSDVT VSCTSLDKDK 120
  121 REEVHKYVQM MGGRVYRDLN VSVTHLIAGE VGSKKYLVAA NLKKPILLPS WIKTLWEKSQ 180
  181 EKKITKYTDV NMEDFKCPIF LGCIICVTGL NGIHRKTVQQ LTAKHGGQYM GQLKMNECTH 240
  241 LIVQEPKGQK YECARRWNVH CVTLQWFHDS IEKGFCQDES IYKAETRVEA KMVPDTSTPT 300
  301 AQSNAESHTL ADVSHISNIN GSCVNETMFG STTSKLECSL ENLENLDISM FQAPEDLLDG 360
  361 CRIYLCGFSG RKLDKLRRLI NSGGGVRFNQ LNEDVTHVIV GDYDDDVRQF WSKSSHRPHV 420
  421 VGAKWLLECF TKGYILPEES YIHTNYQPAG IAVSDQPGNQ TAVLDKSGSF SKSALVPAER 480
  481 LQQADEDLLA QYGNDDSTMV EAKLSEALEP EVGPCPGSAH REPCDDSTHI SVQEENKSSV 540
  541 SHCILDDSTV REEGLFSQKS FLVLGFSVEN KCNIVDIIRE HAGKIVSLPS RIVADYAVVP 600
  601 LLGCEVDVTV GEVVTNTWLV TCIDNQTLVD PKSNPLFTPV SVMSGVTPLE DCVISFSQCV 660
  661 GAERDSLVFL ANHLGASVQE FFVRKANAKK GMLASTHLIV KEPTGSKYEA AKKWSLPAVN 720
  721 ISWLLETARI GKRADENHFL VDNAPKQEQV LETKIPNGVS SNPDLPAHPD AHLEIHRKKA 780
  781 VTPLDMNRFQ SRAFRAVISQ QRGQDPTFPP VRQPLTKEPS LHLDTPSKFL SKDKLFKPSF 840
  841 DVTDALAALE TPNAASQKRK LSSPLSEVIV RNLTVALANS SRNTDSHSAS PQLKGAHLEE 900
  901 EETRKPLDSV VVCVSKKLSK KQSELNGVAA SLGAEYRWSF DETVTHFIYQ GRANDSNREY 960
  961 KSAKERGVHI VSEHWLLECA QEYKHLPESL YPHTYNPKMS LDINTVQDGR LCNSRAPLAV1020
 1021 SASKDDGPDH LSVEGNETNT MGTNDKESPL LNGSGRDDCK GALTQALEMR ENFQKQLQEI1080
 1081 MSATCIVKTP AQKTCMSRSS CNSASSTPDS ARSVRSGRSR VLEALRQSRQ AVPDVNTEPS1140
 1141 QNEQIIWDDP TAREERARLA SNLQWPSDPT QHSELQVEIK MPDDSPSRKP VYHSEIAEQA1200
 1201 SCVTQAPGHP GSEEPEPPVA ERPLIPEPQA PAVASPLAKP PVAPQPADKI ETQEETHRKV1260
 1261 KKQYVFQMSS LNSQERIDYC RLIKDLGGSV IEKQCSDPSC THMVVGYPLR NEKYLASMAA1320
 1321 GKWVLHRSYL DACKTAGRFV QEEDYEWGSS SILDALPDVT EHQQKLALAA MRWRKRIQQS1380
 1381 QESGIVEGAF SGWKAILRVD RPREAGFKRL LQAGGAKVLS GHPEPLLKDA THLFCDFNKL1440
 1441 KPDDCRVFIA EATAQNMVCL KTEYIADYLM LESPPCADNY RVSEAALFHN KKGGPGLPQK1500
 1501 RKTPAENVVK RPRVH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: TOPB1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: