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Protein Overview: ORN_MOUSE

General Information:
Name(s) found: ORN_MOUSE [Swiss-Prot]
Description(s) found:
Found 24 descriptions.
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  • Oligoribonuclease, mitochondrial OS=Mus musculus GN=Rexo2 PE=1 SV=2 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 237 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA]
    intracellular [IEA]
    Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [UNKNOWN]
    Molecular Function: nucleic acid binding [IEA]
    3'-5' exonuclease activity [UNKNOWN]
    exonuclease activity [IEA]
    nuclease activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGVSLGARL LRGVGGRRGQ FGARGVSEGS AAMAAGESMA QRMVWVDLEM TGLDIEKDQI  60
   61 IEMACLITDS DLNILAEGPN LIIKQPDELL DSMSDWCKEH HGKSGLTKAV KESTVTLQQA 120
  121 EYEFLSFVRQ QTPPGLCPLA GNSVHADKKF LDKHMPQFMK HLHYRIIDVS TVKELCRRWY 180
  181 PEDYEFAPKK AASHRALDDI SESIKELQFY RNNIFKKKTD EKKRKIIENG ETEKPVS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..237] PSI-BLAST 41.39794 Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  4.81599779544001 bayes_pls_golite062009
  • exoribonuclease activity
    		•  3.01417328311605 bayes_pls_golite062009
  • ribonuclease H activity
    		•  2.91966688044755 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  2.89077854960958 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.70794511869438 bayes_pls_golite062009
  • nuclease activity
    		•  2.65398446409354 bayes_pls_golite062009
  • endonuclease activity
    		•  2.63074055051349 bayes_pls_golite062009
  • endoribonuclease activity
    		•  2.59247838057313 bayes_pls_golite062009
  • hydrolase activity
    		•  2.41899414621161 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.20855917457806 bayes_pls_golite062009
  • binding
    		•  1.8781442498221 bayes_pls_golite062009
  • endoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.74431545836806 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.72558334058697 bayes_pls_golite062009
  • DNA binding
    		•  1.62101283948059 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.59628511603826 bayes_pls_golite062009
  • exonuclease activity
    		•  1.4327316829508 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  1.42069917818896 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
    		• 1.18236432793831 bayes_pls_golite062009
  • transcription factor activity
    		•  0.971926865662649 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.86862629020506 bayes_pls_golite062009
  • RNA binding
    		•  0.750194803368593 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.389326716045122 bayes_pls_golite062009
  • transcription activator activity
    		•  0.104967281174106 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle