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Protein Overview: IFNG_MOUSE

General Information:
Name(s) found: IFNG_MOUSE [Swiss-Prot]
Description(s) found:
Found 30 descriptions.
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  • Interferon gamma OS=Mus musculus GN=Ifng PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 155 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN][IDA]
    extracellular region [UNKNOWN]
    Biological Process: positive regulation of nitric oxide biosynthetic process [IDA]
    negative regulation of cell proliferation [UNKNOWN]
    positive regulation of peptidyl-serine phosphorylation of STAT protein [UNKNOWN]
    positive regulation of interleukin-1 beta secretion [IMP]
    positive regulation of neuron differentiation [UNKNOWN]
    positive regulation of cell adhesion [UNKNOWN]
    response to virus [UNKNOWN]
    regulation of transcription [IDA]
    positive regulation of tyrosine phosphorylation of Stat1 protein [UNKNOWN]
    positive regulation of MHC class II biosynthetic process [IDA]
    defense response to protozoan [IMP]
    immune response [IEA]
    positive regulation of transcription, DNA-dependent [IDA]
    endoplasmic reticulum unfolded protein response [IDA]
    antigen processing and presentation [IDA]
    positive regulation of synaptic transmission, cholinergic [UNKNOWN]
    regulation of immune response [IDA]
    negative regulation of growth of symbiont during interaction with host [IDA]
    positive regulation of interleukin-6 biosynthetic process [IDA][IMP]
    positive regulation of isotype switching to IgG isotypes [IDA]
    positive regulation of T cell proliferation [IDA]
    regulation of growth [IEA]
    defense response to bacterium [IDA]
    neutrophil apoptosis [IMP]
    regulation of the force of heart contraction [UNKNOWN]
    positive regulation of interleukin-12 production [IDA]
    positive regulation of interleukin-12 biosynthetic process [IDA]
    negative regulation of growth of symbiont in host [IMP]
    inflammatory cell apoptosis [IMP]
    neutrophil chemotaxis [IDA][IMP]
    negative regulation of myelination [IDA]
    positive regulation of chemokine biosynthetic process [IDA][IMP]
    Molecular Function: interferon-gamma receptor binding [IEA]
    cytokine activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNATHCILAL QLFLMAVSGC YCHGTVIESL ESLNNYFNSS GIDVEEKSLF LDIWRNWQKD  60
   61 GDMKILQSQI ISFYLRLFEV LKDNQAISNN ISVIESHLIT TFFSNSKAKK DAFMSIAKFE 120
  121 VNNPQVQRQA FNELIRVVHQ LLPESSLRKR KRSRC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] PSI-BLAST 49.30103 Interferon-gamma


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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