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Any process that modulates the frequency, rate, or extent of a homeostatic process. Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The process by which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process by which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. A organ system process carried out by any of the organs or tissues of neurological system. Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system. Any process that stops, prevents or reduces the frequency, rate or extent of a neurophysiological process. Any process that stops, prevents or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of myelination
Acc: GO:0031642
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
Synonyms:
  • downregulation of myelination
  • down-regulation of myelination
  • inhibition of myelination
  • down regulation of myelination
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031642 - negative regulation of myelination (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle