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Protein Overview: SKP2_MOUSE

General Information:
Name(s) found: SKP2_MOUSE [Swiss-Prot]
Description(s) found:
Found 27 descriptions.
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  • S-phase kinase-associated protein 2 OS=Mus musculus GN=Skp2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 424 amino acids

    Gene Ontology:
    Cellular Component: SCF ubiquitin ligase complex [IDA]
    Biological Process: positive regulation of smooth muscle cell proliferation [UNKNOWN]
    protein polyubiquitination [IDA]
    G1/S transition of mitotic cell cycle [IDA]
    positive regulation of estrogen receptor signaling pathway [IGI]
    regulation of cell cycle [IPI]
    negative regulation of survival gene product expression [IDA]
    ubiquitin-dependent protein catabolic process [IDA]
    Molecular Function: ubiquitin-protein ligase activity [IDA]
    protein binding [IPI]
    kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRKHLQEIP DQSGNVTTSF TWGWDSSKTS ELLSGMGVSA LEKEEVDSEN IPHGLLSNLG  60
   61 HPQSPPRKRV KGKGSDKDFV IIRRPKLSRE NFPGVSWDSL PDELLLGIFS CLCLPELLRV 120
  121 SGVCKRWYRL SLDESLWQSL DLAGKNLHPD VTVRLLSRGV VAFRCPRSFM EQPLGESFSS 180
  181 FRVQHMDLSN SVINVSNLHK ILSECSKLQN LSLEGLQLSD PIVKTLAQNE NLVRLNLCGC 240
  241 SGFSESAVAT LLSSCSRLDE LNLSWCFDFT EKHVQAAVAH LPNTITQLNL SGYRKNLQKT 300
  301 DLCTIIKRCP NLIRLDLSDS IMLKNDCFPE FFQLNYLQHL SLSRCYDIIP DTLLELGEIP 360
  361 TLKTLQVFGI VPEGTLQLLR EALPRLQINC AYFTTIARPT MDSKKNLEIW GIKCRLTLQK 420
  421 PSCL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle