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Protein Overview: PLF4_MOUSE

General Information:
Name(s) found: PLF4_MOUSE [Swiss-Prot]
Description(s) found:
Found 35 descriptions.
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  • Platelet factor 4 OS=Mus musculus GN=Pf4 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 105 amino acids

    Gene Ontology:
    Cellular Component: platelet alpha granule [UNKNOWN]
    extracellular space [IEA]
    vesicle [UNKNOWN]
    protein complex [UNKNOWN]
    extracellular region [IEA]
    Biological Process: chemotaxis [IEA]
    immune response [UNKNOWN]
    protein complex assembly [UNKNOWN]
    Molecular Function: heparin binding [IEA]
    cytokine activity [IEA]
    chemokine activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVAAVFRGL RPSPELLLLG LLFLPAVVAV TSAGPEESDG DLSCVCVKTI SSGIHLKHIT  60
   61 SLEVIKAGRH CAVPQLIATL KNGRKICLDR QAPLYKKVIK KILES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] PSI-BLAST 14.221849 CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytokine activity
    		•  7.36696853209356 bayes_pls_golite062009
  • chemokine receptor binding
    		•  7.19574940007631 bayes_pls_golite062009
  • chemokine activity
    		•  7.19574940007631 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  6.50180912315564 bayes_pls_golite062009
  • receptor binding
    		•  5.70505228637425 bayes_pls_golite062009
  • protein binding
    		•  3.96178206863622 bayes_pls_golite062009
  • binding
    		•  3.65388893211626 bayes_pls_golite062009
  • chemoattractant activity
    		•  3.05299139114464 bayes_pls_golite062009
  • heparin binding
    		•  2.93859357151702 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.81946188257918 bayes_pls_golite062009
  • polysaccharide binding
    		•  2.54793646339608 bayes_pls_golite062009
  • interleukin-8 receptor binding
    		•  2.47283757230168 bayes_pls_golite062009
  • pattern binding
    		•  1.02739535268516 bayes_pls_golite062009
  • transporter activity
    		•  0.37749277737086 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.155507784384114 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.14673741350408 bayes_pls_golite062009
  • catalytic activity
    		•  0.11400259673574 bayes_pls_golite062009
  • CCR chemokine receptor binding
    		•  0.0691884426876317 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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