Protein Overview: C2TA_MOUSE

General Information:
Name(s) found:	C2TA_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6318320\|gb\|AAF06838.1\|AF100709_1 MHC class II transactivator CIITA form I [Mus musculus] [NCBI NR] gi\|30179824\|sp\|P79621.2\|C2TA_MOUSE RecName: Full=MHC class II transactivator; Short=CIITA [NCBI NR] MHC class II transactivator OS=Mus musculus GN=Ciita PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):None Splice isoform 1 of P79621 MHC class II transactivator [hmr_yeast5_DM3-1_pombe.fasta] MHC class II transactivator CIITA form I [Mus musculus]gi\|30179824\|sp\|P79621\|C2TA_MOUSE MHC class II transactivator (CIITA) [nrdb_11152004_Chlamydomonas] Splice Isoform 1 of MHC class II transactivator [ipi.MOUSE.v3.06.fasta] Tax_Id=10090 Splice Isoform 1 of MHC class II transactivator [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] MHC class II transactivator (CIITA) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] MHC class II transactivator CIITA form I [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SPLICE ISOFORM 1 OF MHC CLASS II TRANSACTIVATOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Ciita Isoform 1 of MHC class II transactivator [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=EG669998;Ciita Isoform 1 of MHC class II transactivator ENSMUSG00000075404 IPI00115417 IPI00108982 IPI00655168 IPI00652697 IPI00742270 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00108982.1\|SWISS-PROT:P79621-1\|TREMBL:Q3U2F8;Q3U2P0;Q3UNW8\|ENSEMBL:ENSMUSP00000073732 Tax_Id=10090 Gene_Symbol=Ciita Isoform 1 of MHC class II transactivator [ipi.MOUSE.fasta.20090209] Isoform 1 of MHC class II transactivator OS=Mus musculus GN=Ciita [011711_HMR.fasta] sp\|P79621\|C2TA_MOUSE MHC class II transactivator OS=Mus musculus GN=Ciita PE=2 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	1155 amino acids
Gene Ontology:
Cellular Component:	nucleus [IC]
Biological Process:	transcription [IEA] negative regulation of transcription, DNA-dependent [UNKNOWN] positive regulation of transcription, DNA-dependent [UNKNOWN] negative regulation of transcription [IMP] response to interferon-gamma [IDA] response to antibiotic [UNKNOWN] regulation of transcription [IEA] positive regulation of MHC class II biosynthetic process [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein binding [IEA] transcription regulator activity [IEA] transcription activator activity [UNKNOWN] transcription repressor activity [UNKNOWN][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHFQAILAQ VQTLLSSQKP RQVRALLDGL LEEELLSREY HCALLHEPDG DALARKISLT  60
   61 LLEKGDLDLT FLSWVCNSLQ APTVERGTSY RDHGDHSLCA TMDLGSPEGS YLELLNSDAD 120
  121 PLHLYHLYDQ MDLAGEEEIE LSSEPDTDTI NCDQFSKLLQ DMELDEETRE AYANIAELDQ 180
  181 YVFQDTQLEG LSKDLFIEHI GAEEGFGENI EIPVEAGQKP QKRRFPEEHA MDSKHRKLVP 240
  241 TSRTSLNYLD LPTGHIQIFT TLPQGLWQIS GAGTGLSSVL IYHGEMPQVN QVLPSSSLSI 300
  301 PSLPESPDRP GSTSPFTPSA ADLPSMPEPA LTSRVNETED TSPSPCQEGP ESSIKLPKWP 360
  361 EAVERFQHSL QDKYKALPQS PRGPLVAVEL VRARLERGSN KSQERELATP DWTERQLAHG 420
  421 GLAEVLQVVS DCRRPGETQV VAVLGKAGQG KSHWARTVSH TWACGQLLQY DFVFYVPCHC 480
  481 LDRPGDTYHL RDLLCPPSLQ PLAMDDEVLD YIVRQPDRVL LILDAFEELE AQDGLLHGPC 540
  541 GSLSPEPCSL RGLLAGIFQR KLLRGCTLLL TARPRGRLAQ SLSKADAIFE VPSFSTKQAK 600
  601 TYMRHYFENS GTAGNQDKAL GLLEGQPLLC SYSHSPVVCR AVCQLSKALL EQGTEAQLPC 660
  661 TLTGLYVSLL GPAAQNSPPG ALVELAKLAW ELGRRHQSTL QETRFSSVEV KTWAVTQGLM 720
  721 QQTLETTEAQ LAFSSFLLQC FLGAVWLAQC NEIKDKELPQ YLALTPRKKR PYDNWLEGVP 780
  781 RFLAGLVFQP RAHCLGALVE PAVAAVADRK QKVLTRYLKR LKLGTLRAGR LLELLHCAHE 840
  841 TQQPGIWEHV AHQLPGHLSF LGTRLTPPDV YVLGRALETA SQDFSLDLRQ TGVEPSGLGN 900
  901 LVGLSCVTSF RASLSDTMAL WESLQQQGEA QLLQAAEEKF TIEPFKAKSP KDVEDLDRLV 960
  961 QTQRLRNPSE DAAKDLPAIR DLKKLEFALG PILGPQAFPT LAKILPAFSS LQHLDLDSLS1020
 1021 ENKIGDKGVS KLSATFPQLK ALETLNLSQN NITDVGACKL AEALPALAKS LLRLSLYNNC1080
 1081 ICDKGAKSLA QVLPDMVSLR VMDVQFNKFT AAGAQQLASS LQKCPQVETL AMWTPTIPFG1140
 1141 VQEHLQQLDA RISLR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.63

Protein Overview: C2TA_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: