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Protein Overview: TNFL4_MOUSE

General Information:
Name(s) found: TNFL4_MOUSE [Swiss-Prot]
Description(s) found:
Found 27 descriptions.
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  • Tumor necrosis factor ligand superfamily member 4 OS=Mus musculus GN=Tnfsf4 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 198 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IEA]
    membrane [IEA]
    integral to membrane [IEA]
    cell surface [UNKNOWN]
    Biological Process: inflammatory response [IPI]
    positive regulation of immunoglobulin secretion [IDA]
    immune response [IEA]
    negative regulation of gene-specific transcription [IDA]
    T cell proliferation [UNKNOWN]
    cholesterol metabolic process [IMP]
    cytokine production [UNKNOWN]
    negative regulation of transcription factor activity [IDA]
    negative regulation of cytokine secretion [IPI]
    Molecular Function: tumor necrosis factor receptor superfamily binding [UNKNOWN][IPI]
    protein binding [IPI]
    tumor necrosis factor receptor binding [UNKNOWN][IPI]
    cytokine activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGEGVQPLD ENLENGSRPR FKWKKTLRLV VSGIKGAGML LCFIYVCLQL SSSPAKDPPI  60
   61 QRLRGAVTRC EDGQLFISSY KNEYQTMEVQ NNSVVIKCDG LYIIYLKGSF FQEVKIDLHF 120
  121 REDHNPISIP MLNDGRRIVF TVVASLAFKD KVYLTVNAPD TLCEHLQIND GELIVVQLTP 180
  181 GYCAPEGSYH STVNQVPL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..198] PSI-BLAST 75.221849 No description for 2hewF was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • tumor necrosis factor receptor binding
    		•  4.97032095500332 bayes_pls_golite062009
  • tumor necrosis factor receptor superfamily binding
    		•  2.83043724362524 bayes_pls_golite062009
  • receptor binding
    		•  2.30826967264465 bayes_pls_golite062009
  • protein binding
    		•  2.25413201891408 bayes_pls_golite062009
  • CD40 receptor binding
    		•  1.92939268560534 bayes_pls_golite062009
  • binding
    		•  1.55055236820725 bayes_pls_golite062009
  • cell surface binding
    		•  1.54737106887049 bayes_pls_golite062009
  • eukaryotic cell surface binding
    		•  1.02834426035531 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle