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Protein Overview: S5A2_MOUSE

General Information:
Name(s) found: S5A2_MOUSE [Swiss-Prot]
Description(s) found:
Found 27 descriptions.
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  • 3-oxo-5-alpha-steroid 4-dehydrogenase 2 OS=Mus musculus GN=Srd5a2 PE=2 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 254 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    membrane [IEA]
    microsome [IEA]
    integral to membrane [IEA]
    endoplasmic reticulum [IEA]
    cellular_component [ND]
    Biological Process: sex differentiation [IEA]
    response to organic substance [UNKNOWN]
    androgen biosynthetic process [IMP]
    male genitalia development [IMP]
    response to drug [UNKNOWN]
    lipid metabolic process [IEA]
    steroid catabolic process [UNKNOWN]
    cell differentiation [IEA]
    steroid metabolic process [IEA]
    oxidation reduction [IEA]
    steroid biosynthetic process [UNKNOWN][IMP]
    response to peptide hormone stimulus [UNKNOWN]
    Molecular Function: 3-oxo-5-alpha-steroid 4-dehydrogenase activity [UNKNOWN][IMP]
    oxidoreductase activity, acting on the CH-CH group of donors [IEA]
    oxidoreductase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIVCHQVPV LAGSATLATM GTLILCFGKP ASYGKHSESV SSGVPLLPAR IAWFLQELPS  60
   61 FVVSVGMLAW QPRSLFGPPG NVLLGLFSAH YFHRTFIYSL LTRGRPLSAV IFLKATAFCI 120
  121 GNGLLQAYYL VYCAEYPEEW YTDMRFSVGV FFFILGMGIN IHSDCMLRQL RKPGEVIYRI 180
  181 PQGGLFTYVS GANFLGEIIE WMGYALATWS VPAFAFAFFT LCFLGMQAFY HHRFYLKMFK 240
  241 DYPKSRKALI PFIF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..70] MSA 2.188993 View MSA. No confident structure predictions are available.
    2 View Details [71..254] Pfam 85.031517 No description for PF02544.7 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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