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Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 3-oxo-5-alpha-steroid 4-dehydrogenase activity
Acc: GO:0003865
Aspect: Molecular Function
Desc: Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor.
Synonyms:
  • testosterone 5alpha-reductase
  • 3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase activity
  • delta4-3-keto steroid 5alpha-reductase activity
  • delta4-3-oxosteroid-5alpha-reductase
  • steroid 5alpha-reductase
  • 3-oxo-5alpha-steroid 4-dehydrogenase activity
  • delta4-3-oxo steroid reductase activity
  • 3-keto-delta4-steroid-5alpha-reductase activity
  • 3-oxo-5alpha-steroid delta4-dehydrogenase activity
  • 3-oxo-5alpha-steroid:acceptor delta4-oxidoreductase activity
  • 4-ene-3-ketosteroid-5alpha-oxidoreductase activity
  • steroid 5 alpha reductase
  • 3-oxosteroid delta4-dehydrogenase
  • steroid 5-alpha-reductase activity
  • delta4-3-ketosteroid5alpha-oxidoreductase activity
  • steroid delta4-5alpha-reductase activity
  • delta4-5alpha-dehydrogenase activity
  • 5alpha-reductase
Proteins in PDR annotated with:
   This term: 19 [Search]
   Term or descendants: 19 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003865 - 3-oxo-5-alpha-steroid 4-dehydrogenase activity (interactive image map)
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