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Protein Overview: DYR_MOUSE

General Information:
Name(s) found: DYR_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|74200104|dbj|BAE22879.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|7106289|ref|NP_034179.1| dihydrofolate reductase [Mus musculus] [NCBI NR]
  • gi|439209|gb|AAA37523.1| dihydrofolate reductase [Mus musculus] [NCBI NR]
  • gi|387160|gb|AAA37638.1| dihydrofolate reductase [Mus musculus] [NCBI NR]
  • gi|26327143|dbj|BAC27315.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|1706542|sp|P00375.3|DYR_MOUSE RecName: Full=Dihydrofolate reductase [NCBI NR]
  • gi|148668639|gb|EDL00958.1| dihydrofolate reductase [Mus musculus] [NCBI NR]
  • gi|13543257|gb|AAH05796.1| Dihydrofolate reductase [Mus musculus] [NCBI NR]
  • Dihydrofolate reductase OS=Mus musculus GN=Dhfr PE=1 SV=3 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):13-88696002 dihydrofolate reductase [hmr_yeast5_DM3-1_pombe.fasta]
  • dihydrofolate reductase [HMR_022704-rand.fasta]
  • dihydrofolate reductase [Mus musculus]gi|387160|gb|AAA37638.1| dihydrofolate reductase [Mus musculus]gi|13543257|gb|AAH05796.1| Dihydrofolate reductase [Mus musculus]gi|439209|gb|AAA37523.1| dihydrofolate reductase [Mus musculus]gi|1706542|sp|P00375|D [nrdb_11152004_Chlamydomonas]
  • (NM_010049) dihydrofolate reductase [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • dihydrofolate reductase [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Dihydrofolate reductase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Dihydrofolate reductase [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 DIHYDROFOLATE REDUCTASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Dhfr Dihydrofolate reductase [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Dhfr Dihydrofolate reductase ENSMUSG00000021707 IPI00230042 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • IPI:IPI00230042.5|SWISS-PROT:P00375|TREMBL:Q544T5|ENSEMBL:ENSMUSP00000022218|REFSEQ:NP_034179 Tax_Id=10090 Gene_Symbol=Dhfr Dihydrofolate reductase [ipi.MOUSE.fasta.20090209]
  • Dihydrofolate reductase OS=Mus musculus GN=Dhfr [011711_HMR.fasta]
  • sp|P00375|DYR_MOUSE Dihydrofolate reductase OS=Mus musculus GN=Dhfr PE=1 SV=3 [uniprot.sptr.mouse.20130102]
  • tr|Q544T5|Q544T5_MOUSE Dihydrofolate reductase OS=Mus musculus GN=Dhfr PE=2 SV=1 [uniprot.sptr.mouse.20130102]
  • Dihydrofolate reductase OS=Mus musculus GN=Dhfr PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
  • Isoform of P00375, Dihydrofolate reductase OS=Mus musculus GN=Dhfr PE=1 SV=1 [MOUSE.fasta.20160308]
    • Organism: Mus musculus
    Length: 187 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [UNKNOWN]
    Biological Process: response to methotrexate [IEA]
    nucleotide biosynthetic process [IEA]
    dihydrofolate metabolic process [UNKNOWN]
    oxidation reduction [IEA]
    tetrahydrofolate biosynthetic process [UNKNOWN]
    glycine biosynthetic process [IEA]
    one-carbon metabolic process [IEA]
    Molecular Function: NADP or NADPH binding [UNKNOWN]
    dihydrofolic acid binding [UNKNOWN]
    oxidoreductase activity [IEA]
    dihydrofolate reductase activity [UNKNOWN][IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRPLNCIVA VSQNMGIGKN GDLPWPPLRN EFKYFQRMTT TSSVEGKQNL VIMGRKTWFS  60
   61 IPEKNRPLKD RINIVLSREL KEPPRGAHFL AKSLDDALRL IEQPELASKV DMVWIVGGSS 120
  121 VYQEAMNQPG HLRLFVTRIM QEFESDTFFP EIDLGKYKLL PEYPGVLSEV QEEKGIKYKF 180
  181 EVYEKKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..187] PSI-BLAST 62.30103 No description for 2fzjA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle