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Protein Overview: DYR_MOUSE

General Information:
Name(s) found: DYR_MOUSE [Swiss-Prot]
Description(s) found:
Found 26 descriptions.
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  • Dihydrofolate reductase OS=Mus musculus GN=Dhfr PE=1 SV=3 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 187 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [UNKNOWN]
    Biological Process: response to methotrexate [IEA]
    nucleotide biosynthetic process [IEA]
    dihydrofolate metabolic process [UNKNOWN]
    oxidation reduction [IEA]
    tetrahydrofolate biosynthetic process [UNKNOWN]
    glycine biosynthetic process [IEA]
    one-carbon metabolic process [IEA]
    Molecular Function: NADP or NADPH binding [UNKNOWN]
    dihydrofolic acid binding [UNKNOWN]
    oxidoreductase activity [IEA]
    dihydrofolate reductase activity [UNKNOWN][IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRPLNCIVA VSQNMGIGKN GDLPWPPLRN EFKYFQRMTT TSSVEGKQNL VIMGRKTWFS  60
   61 IPEKNRPLKD RINIVLSREL KEPPRGAHFL AKSLDDALRL IEQPELASKV DMVWIVGGSS 120
  121 VYQEAMNQPG HLRLFVTRIM QEFESDTFFP EIDLGKYKLL PEYPGVLSEV QEEKGIKYKF 180
  181 EVYEKKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..187] PSI-BLAST 62.30103 No description for 2fzjA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle