Protein Overview: PEO1_MOUSE

General Information:
Name(s) found:	PEO1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|78099072\|sp\|Q8CIW5.1\|PEO1_MOUSE RecName: Full=Twinkle protein, mitochondrial; AltName: Full=T7 gp4-like protein with intramitochondrial nucleoid localization; AltName: Full=T7-like mitochondrial DNA helicase; AltName: Full=Progressive external ophthalm [NCBI NR] gi\|74226718\|dbj\|BAE27008.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|48734593\|gb\|AAH71195.1\| Progressive external ophthalmoplegia 1 (human) [Mus musculus] [NCBI NR] gi\|24962647\|ref\|NP_722491.2\| twinkle [Mus musculus] [NCBI NR] gi\|24473770\|gb\|AAL27647.1\| Twinkle [Mus musculus] [NCBI NR] gi\|148709998\|gb\|EDL41944.1\| progressive external ophthalmoplegia 1 (human) [Mus musculus] [NCBI NR] Twinkle protein, mitochondrial OS=Mus musculus GN=Peo1 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):19-44650750 Twinkle [hmr_yeast5_DM3-1_pombe.fasta] twinkle; T7 gp4-like protein with intramitochondrial nucleoid localization [HMR_022704-rand.fasta] Twinkle [ipi.MOUSE.v3.06.fasta] twinkle [Mus musculus]gi\|48734593\|gb\|AAH71195.1\| Twinkle [Mus musculus]gi\|24473770\|gb\|AAL27647.1\| Twinkle [Mus musculus] [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Splice Isoform 1 of Twinkle protein, mitochondrial precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] twinkle [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 Twinkle [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] Twinkle protein, mitochondrial precursor (T7 gp4-like protein with intramitochondrial nucleoid localization) (T7-like mitochondrial DNA helicase) (Progressive external ophthalmoplegia 1 protein homolog) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] progressive external ophthalmoplegia 1 (human) [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Progressive external ophthalmoplegia 1 (human) [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Twinkle [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 TWINKLE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Peo1 Isoform 1 of Twinkle protein, mitochondrial [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Peo1 Isoform 1 of Twinkle protein, mitochondrial precursor [ipi.MOUSE_jw_12may08.contam.fasta] Tax_Id=10090 Gene_Symbol=Peo1 Isoform 1 of Twinkle protein, mitochondrial precursor ENSMUSG00000025209 IPI00229939 IPI00655230 IPI00652328 [IPIxENS.MOUSE_plus_REVERSE.fasta] twinkle protein, mitochondrial [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00229939.1\|SWISS-PROT:Q8CIW5-1\|TREMBL:Q80WJ5\|ENSEMBL:ENSMUSP00000026227\|REFSEQ:NP_722491 Tax_Id=10090 Gene_Symbol=Peo1 Isoform 1 of Twinkle protein, mitochondrial [ipi.MOUSE.fasta.20090209] Isoform 1 of Twinkle protein, mitochondrial OS=Mus musculus GN=Peo1 [011711_HMR.fasta] sp\|Q8CIW5\|PEO1_MOUSE Twinkle protein, mitochondrial OS=Mus musculus GN=Peo1 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	685 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA]
Biological Process:	DNA replication [IEA] mitochondrial DNA replication [IMP] DNA unwinding involved in replication [IDA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] DNA helicase activity [UNKNOWN][IDA] helicase activity [IEA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWLLLRRAYP LRILLPLRGE WVGRRGLPRS LAPGPPRRRY RKEALPALEM PVSPVTTTEI  60
   61 RQYLRAHGIP FQDGHSCLRA PSPFVVSSDI KNEKKDAPTS FCLFIDKTTG HFLCMTSLAE 120
  121 GSWEDLQASV EGRGDGAKEG VLLREGPEAE VREEVLRIWN RAIPLWELPD PEEAQLARVM 180
  181 FGLTKVTDDT LRRFSVRYLR SARSLVFPWF TPGSSGLRGL KLLGAEGQEN GVQYVETTIP 240
  241 RPGVYHNLFG LPLISRRDTE VVVTSRELDS LALSQSTGLP TLSLPRGTVC LPPALLPYLE 300
  301 QFRRIVFWLG DDLRSWEAAK LFARKLNPKR CSLVRPGNQQ PRPLEALNQG LSLPRILRTA 360
  361 LPAWHKSIVS FRQLREEVLG ELSNVEQAAG VRWSRFPDLN RLLKGHRKGE LTVFTGPTGS 420
  421 GKTTFISEYA LDLCTQGVNT LWGSFEISNV RLARVMLTQF AVTRLEEQLD KYEEWADRFE 480
  481 DLPLYFMTFH GQQSIRSVID TMQHAVYVYD VCHVVIDNLQ FMMGHEQLSS DRIAAQDYIV 540
  541 GAFRKFATDN SCHVTLVIHP RKEDDDKELQ TASIFGSAKA SQEADNVLIL QDRKLVTGPG 600
  601 KRYLQVSKNR FDGDVGVFPL EFNKNSLTFS IPPKSKARLK KIKDDNGLVA KKSSSGKKGA 660
  661 AHQNPEICLG QDPSPAQPDT SKSSG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: PEO1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: