Protein Overview: SIX1_MOUSE

General Information:
Name(s) found:	SIX1_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|74203436\|dbj\|BAE20875.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|46397863\|sp\|Q62231.2\|SIX1_MOUSE RecName: Full=Homeobox protein SIX1; AltName: Full=Sine oculis homeobox homolog 1 [NCBI NR] gi\|23273881\|gb\|AAH23304.1\| Sine oculis-related homeobox 1 homolog (Drosophila) [Mus musculus] [NCBI NR] gi\|226958387\|ref\|NP_033215.2\| sine oculis homeobox homolog 1 [Mus musculus] [NCBI NR] Homeobox protein SIX1 OS=Mus musculus GN=Six1 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):12-67689821 Sine oculis homeobox homolog 1 [hmr_yeast5_DM3-1_pombe.fasta] Homeobox protein SIX1 [ipi.MOUSE.v3.06.fasta] sine oculis homeobox homolog 1 [Rattus norvegicus]gi\|23273881\|gb\|AAH23304.1\| Sine oculis homeobox homolog 1 [Mus musculus]gi\|46397863\|sp\|Q62231\|SIX1_MOUSE Homeobox protein SIX1 (Sine oculis homeobox homolog 1) [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Homeobox protein SIX1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] Homeobox protein SIX1 (Sine oculis homeobox homolog 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Sine oculis-related homeobox 1 homolog (Drosophila) [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 HOMEOBOX PROTEIN SIX1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Six1 Homeobox protein SIX1 [mouse-ipi-250309-contam.fasta] sine oculis homeobox homolog 1 [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Six1 Homeobox protein SIX1 ENSMUSG00000051367 IPI00229876 [IPIxENS.MOUSE_plus_REVERSE.fasta] homeobox protein SIX1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00229876.1\|SWISS-PROT:Q62231\|TREMBL:Q3V2C3;Q8BSP4\|ENSEMBL:ENSMUSP00000059026\|REFSEQ:NP_033215 Tax_Id=10090 Gene_Symbol=Six1 Homeobox protein SIX1 [ipi.MOUSE.fasta.20090209] Homeobox protein SIX1 OS=Mus musculus GN=Six1 [011711_HMR.fasta] sp\|Q62231\|SIX1_MOUSE Homeobox protein SIX1 OS=Mus musculus GN=Six1 PE=1 SV=2 [uniprot.sptr.mouse.20130102] tr\|Q3V2C3\|Q3V2C3_MOUSE Putative uncharacterized protein OS=Mus musculus GN=Six1 PE=2 SV=1 [uniprot.sptr.mouse.20130102] Putative uncharacterized protein OS=Mus musculus GN=Six1 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta] Isoform of Q62231, Homeobox protein SIX1 OS=Mus musculus GN=Six1 PE=2 SV=1 [MOUSE.fasta.20160308]
Organism:	Mus musculus
Length:	284 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] transcription factor complex [IDA][IPI]
Biological Process:	inner ear development [IMP] transcription [IEA] multicellular organismal development [IEA] anatomical structure development [IGI] pattern specification process [IGI] regulation of transcription, DNA-dependent [IDA] regulation of neuron differentiation [IMP] generation of neurons [IMP] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [IDA] embryonic skeletal system morphogenesis [IGI] thymus development [IGI][IMP] negative regulation of neuron apoptosis [IMP] epithelial cell differentiation [IMP] thyroid gland development [IMP] myoblast migration [IGI] ureteric bud development [IGI][IMP] kidney development [IMP] branching involved in ureteric bud morphogenesis [IGI] skeletal muscle tissue development [IGI] inner ear morphogenesis [IGI] induction of an organ [IMP]
Molecular Function:	DNA binding [IEA] transcription factor activity [IDA] protein binding [IPI] transcription regulator activity [IEA] sequence-specific DNA binding [IDA] chromatin binding [IGI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMLPSFGFT QEQVACVCEV LQQGGNLERL GRFLWSLPAC DHLHKNESVL KAKAVVAFHR  60
   61 GNFRELYKIL ESHQFSPHNH PKLQQLWLKA HYVEAEKLRG RPLGAVGKYR VRRKFPLPRT 120
  121 IWDGEETSYC FKEKSRGVLR EWYAHNPYPS PREKRELAEA TGLTTTQVSN WFKNRRQRDR 180
  181 AAEAKERENT ENNNSSSNKQ NQLSPLEGGK PLMSSSEEEF SPPQSPDQNS VLLLQSNMGH 240
  241 ARSSNYSLPG LTASQPSHGL QAHQHQLQDS LLGPLTSSLV DLGS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: SIX1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: