Protein Overview: SIX1_MOUSE

General Information:
Name(s) found:	SIX1_MOUSE [Swiss-Prot]
Description(s) found: Found 23 descriptions. SHOW ALL	Homeobox protein SIX1 OS=Mus musculus GN=Six1 PE=1 SV=2 [Swiss-Prot]
Organism:	Mus musculus
Length:	284 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] transcription factor complex [IDA][IPI]
Biological Process:	inner ear development [IMP] transcription [IEA] multicellular organismal development [IEA] anatomical structure development [IGI] pattern specification process [IGI] regulation of transcription, DNA-dependent [IDA] regulation of neuron differentiation [IMP] generation of neurons [IMP] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [IDA] embryonic skeletal system morphogenesis [IGI] thymus development [IGI][IMP] negative regulation of neuron apoptosis [IMP] epithelial cell differentiation [IMP] thyroid gland development [IMP] myoblast migration [IGI] ureteric bud development [IGI][IMP] kidney development [IMP] branching involved in ureteric bud morphogenesis [IGI] skeletal muscle tissue development [IGI] inner ear morphogenesis [IGI] induction of an organ [IMP]
Molecular Function:	DNA binding [IEA] transcription factor activity [IDA] protein binding [IPI] transcription regulator activity [IEA] sequence-specific DNA binding [IDA] chromatin binding [IGI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMLPSFGFT QEQVACVCEV LQQGGNLERL GRFLWSLPAC DHLHKNESVL KAKAVVAFHR  60
   61 GNFRELYKIL ESHQFSPHNH PKLQQLWLKA HYVEAEKLRG RPLGAVGKYR VRRKFPLPRT 120
  121 IWDGEETSYC FKEKSRGVLR EWYAHNPYPS PREKRELAEA TGLTTTQVSN WFKNRRQRDR 180
  181 AAEAKERENT ENNNSSSNKQ NQLSPLEGGK PLMSSSEEEF SPPQSPDQNS VLLLQSNMGH 240
  241 ARSSNYSLPG LTASQPSHGL QAHQHQLQDS LLGPLTSSLV DLGS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: SIX1_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: