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Protein Overview: PR2C2_MOUSE

General Information:
Name(s) found: PR2C2_MOUSE [Swiss-Prot]
Description(s) found:
Found 33 descriptions.
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  • Prolactin-2C2 OS=Mus musculus GN=Prl2c2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 224 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IDA]
    endoplasmic reticulum [IDA]
    extracellular region [IEA]
    Biological Process: negative regulation of myoblast differentiation [IDA]
    sprouting angiogenesis [IDA]
    positive regulation of neuroblast proliferation [IDA]
    positive regulation of transcription from RNA polymerase II promoter [IDA]
    positive regulation of angiogenesis [IDA]
    positive regulation of blood vessel endothelial cell migration [IDA]
    regulation of microvillus assembly [IDA]
    positive regulation of cell projection organization [IDA]
    Molecular Function: growth factor activity [IDA]
    protein binding [IPI]
    hormone activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPSLIQPCS WILLLLLVNS SLLWKNVASF PMCAMRNGRC FMSFEDTFEL AGSLSHNISI  60
   61 EVSELFTEFE KHYSNVSGLR DKSPMRCNTS FLPTPENKEQ ARLTHYSALL KSGAMILDAW 120
  121 ESPLDDLVSE LSTIKNVPDI IISKATDIKK KINAVRNGVN ALMSTMLQNG DEEKKNPAWF 180
  181 LQSDNEDARI HSLYGMISCL DNDFKKVDIY LNVLKCYMLK IDNC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..224] PSI-BLAST 66.522879 Prolactin (placental lactogen)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytokine receptor binding
    		•  6.47223189691244 bayes_pls_golite062009
  • receptor binding
    		•  5.3304255990112 bayes_pls_golite062009
  • cytokine activity
    		•  5.1883241815362 bayes_pls_golite062009
  • growth factor activity
    		•  4.92105782010612 bayes_pls_golite062009
  • prolactin receptor binding
    		•  4.15199297607294 bayes_pls_golite062009
  • protein binding
    		•  3.52041127390038 bayes_pls_golite062009
  • growth hormone activity
    		•  3.48964024373018 bayes_pls_golite062009
  • binding
    		•  2.95468228480505 bayes_pls_golite062009
  • hormone activity
    		•  2.52921243340076 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.65758440572832 bayes_pls_golite062009
  • interleukin-27 binding
    		•  1.65090888783496 bayes_pls_golite062009
  • ciliary neurotrophic factor receptor binding
    		•  1.59946630359187 bayes_pls_golite062009
  • interleukin-6 receptor binding
    		•  1.35761970306312 bayes_pls_golite062009
  • interleukin-10 receptor binding
    		•  1.21666375770079 bayes_pls_golite062009
  • interferon-alpha/beta receptor binding
    		•  0.93290045827216 bayes_pls_golite062009
  • erythropoietin receptor binding
    		•  0.5867301437183 bayes_pls_golite062009
  • interleukin-12 binding
    		•  0.30601802121141 bayes_pls_golite062009
  • catalytic activity
    		•  0.246169290135575 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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