Protein Overview: NTRK2_MOUSE

General Information:
Name(s) found:	NTRK2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|74184515\|dbj\|BAE27880.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|74144289\|dbj\|BAE36012.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|68215970\|ref\|NP_001020245.1\| neurotrophic tyrosine kinase, receptor, type 2 isoform a [Mus musculus] [NCBI NR] gi\|136237\|sp\|P15209.1\|NTRK2_MOUSE RecName: Full=BDNF/NT-3 growth factors receptor; AltName: Full=Neurotrophic tyrosine kinase receptor type 2; AltName: Full=TrkB tyrosine kinase; AltName: Full=GP145-TrkB/GP95-TrkB; Short=Trk-B; Flags: Precursor [NCBI NR] pir\|\|S06943 brain-derived neurotrophic factor receptor precursor - mouse [NCBI NR] (P15209) BDNF/NT-3 growth factors receptor precursor (EC 2.7.1.112) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) [Swiss-Prot] BDNF/NT-3 growth factors receptor OS=Mus musculus GN=Ntrk2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):None Splice isoform GP145-TRKB of P15209 BDNF/NT-3 growth factors receptor precursor [hmr_yeast5_DM3-1_pombe.fasta] unnamed protein product [Mus sp.]gi\|136237\|sp\|P15209\|TRKB_MOUSE BDNF/NT-3 growth factors receptor precursor (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B)gi\|111211\|pir\|\|S06943 brain-derived neurotrophic factor receptor precursor - mouse [nrdb_11152004_Chlamydomonas] Splice Isoform GP145-TRKB of BDNF/NT-3 growth factors receptor precursor [ipi.MOUSE.v3.06.fasta] Tax_Id=10090 Splice Isoform GP145-TRKB of BDNF/NT-3 growth factors receptor precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] neurotrophic tyrosine kinase, receptor, type 2 isoform a [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] BDNF/NT-3 growth factors receptor precursor (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SPLICE ISOFORM 1 OF BDNF/NT-3 GROWTH FACTORS RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Ntrk2 Isoform GP145-TRKB of BDNF/NT-3 growth factors receptor [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Ntrk2 Isoform GP145-TRKB of BDNF/NT-3 growth factors receptor precursor [ipi.MOUSE_jw_12may08.contam.fasta] Tax_Id=10090 Gene_Symbol=Ntrk2 Isoform GP145-TRKB of BDNF/NT-3 growth factors receptor precursor ENSMUSG00000055254 IPI00128360 IPI00270098 IPI00229334 IPI00229333 [IPIxENS.MOUSE_plus_REVERSE.fasta] BDNF/NT-3 growth factors receptor isoform a [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00128360.1\|SWISS-PROT:P15209-1\|ENSEMBL:ENSMUSP00000077623;ENSMUSP00000078757\|REFSEQ:NP_001020245 Tax_Id=10090 Gene_Symbol=Ntrk2 Isoform GP145-TRKB of BDNF/NT-3 growth factors receptor [ipi.MOUSE.fasta.20090209] Isoform GP145-TRKB of BDNF/NT-3 growth factors receptor OS=Mus musculus GN=Ntrk2 [011711_HMR.fasta] sp\|P15209\|NTRK2_MOUSE BDNF/NT-3 growth factors receptor OS=Mus musculus GN=Ntrk2 PE=1 SV=1 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	821 amino acids
Gene Ontology:
Cellular Component:	postsynaptic density [UNKNOWN] excitatory synapse [UNKNOWN] neuronal cell body [UNKNOWN] axon terminus [UNKNOWN] plasma membrane [UNKNOWN][IDA] cell surface [UNKNOWN] growth cone [UNKNOWN] integral to plasma membrane [IEA] dendrite [UNKNOWN] presynaptic active zone [UNKNOWN] terminal button [IDA] dendritic spine [UNKNOWN] membrane [IEA] integral to membrane [IEA] cytosol [IDA] axon [UNKNOWN]
Biological Process:	regulation of neurotransmitter secretion [UNKNOWN] glutamate secretion [IPI] multicellular organismal development [IEA] nervous system development [IEA] transmembrane receptor protein tyrosine kinase signaling pathway [IEA] protein amino acid autophosphorylation [UNKNOWN] feeding behavior [IMP] vasculogenesis [IMP] protein amino acid phosphorylation [IEA] retinal rod cell development [IMP] regulation of dendrite development [UNKNOWN] brain-derived neurotrophic factor receptor signaling pathway [UNKNOWN] mechanoreceptor differentiation [IMP] cell differentiation [IEA] regulation of metabolic process [IMP] positive regulation of synaptic transmission, glutamatergic [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein tyrosine kinase activity [IEA] protein binding [IPI] transmembrane receptor protein tyrosine kinase activity [UNKNOWN] neurotrophin receptor activity [UNKNOWN] protein kinase activity [IEA] brain-derived neurotrophic factor binding [UNKNOWN] transferase activity [IEA] receptor activity [IEA] kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPWLKWHGP AMARLWGLCL LVLGFWRASL ACPTSCKCSS ARIWCTEPSP GIVAFPRLEP  60
   61 NSVDPENITE ILIANQKRLE IINEDDVEAY VGLRNLTIVD SGLKFVAYKA FLKNSNLRHI 120
  121 NFTRNKLTSL SRRHFRHLDL SDLILTGNPF TCSCDIMWLK TLQETKSSPD TQDLYCLNES 180
  181 SKNMPLANLQ IPNCGLPSAR LAAPNLTVEE GKSVTLSCSV GGDPLPTLYW DVGNLVSKHM 240
  241 NETSHTQGSL RITNISSDDS GKQISCVAEN LVGEDQDSVN LTVHFAPTIT FLESPTSDHH 300
  301 WCIPFTVRGN PKPALQWFYN GAILNESKYI CTKIHVTNHT EYHGCLQLDN PTHMNNGDYT 360
  361 LMAKNEYGKD ERQISAHFMG RPGVDYETNP NYPEVLYEDW TTPTDIGDTT NKSNEIPSTD 420
  421 VADQSNREHL SVYAVVVIAS VVGFCLLVML LLLKLARHSK FGMKGPASVI SNDDDSASPL 480
  481 HHISNGSNTP SSSEGGPDAV IIGMTKIPVI ENPQYFGITN SQLKPDTFVQ HIKRHNIVLK 540
  541 RELGEGAFGK VFLAECYNLC PEQDKILVAV KTLKDASDNA RKDFHREAEL LTNLQHEHIV 600
  601 KFYGVCVEGD PLIMVFEYMK HGDLNKFLRA HGPDAVLMAE GNPPTELTQS QMLHIAQQIA 660
  661 AGMVYLASQH FVHRDLATRN CLVGENLLVK IGDFGMSRDV YSTDYYRVGG HTMLPIRWMP 720
  721 PESIMYRKFT TESDVWSLGV VLWEIFTYGK QPWYQLSNNE VIECITQGRV LQRPRTCPQE 780
  781 VYELMLGCWQ REPHTRKNIK SIHTLLQNLA KASPVYLDIL G

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: NTRK2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: