Protein Overview: OGA_MOUSE

General Information:
Name(s) found:	OGA_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81881853\|sp\|Q9EQQ9.2\|NCOAT_MOUSE RecName: Full=Bifunctional protein NCOAT; AltName: Full=Nuclear cytoplasmic O-GlcNAcase and acetyltransferase; AltName: Full=Meningioma-expressed antigen 5; Includes: RecName: Full=Beta-hexosaminidase; AltName: Full=N-a [NCBI NR] gi\|32767127\|gb\|AAH54821.1\| Meningioma expressed antigen 5 (hyaluronidase) [Mus musculus] [NCBI NR] gi\|15011884\|ref\|NP_076288.1\| meningioma expressed antigen 5 (hyaluronidase) [Mus musculus] [NCBI NR] gi\|148710022\|gb\|EDL41968.1\| meningioma expressed antigen 5 (hyaluronidase) [Mus musculus] [NCBI NR] gi\|14329484\|gb\|AAG43273.2\|AF132214_1 cytosolic beta-N-acetylglucosaminidase [Mus musculus] [NCBI NR] Protein O-GlcNAcase OS=Mus musculus GN=Mgea5 PE=1 SV=2 [Swiss-Prot] Bifunctional protein NCOAT OS=Mus musculus GN=Mgea5 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):19-45402541 Cytosolic beta-N-acetylglucosaminidase [hmr_yeast5_DM3-1_pombe.fasta] meningioma expressed antigen 5 (hyaluronidase) [HMR_022704-rand.fasta] meningioma expressed antigen 5 (hyaluronidase) [Mus musculus]gi\|32767127\|gb\|AAH54821.1\| Meningioma expressed antigen 5 (hyaluronidase) [Mus musculus]gi\|14329484\|gb\|AAG43273.2\| cytosolic beta-N-acetylglucosaminidase [Mus musculus] [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Cytosolic beta-N-acetylglucosaminidase [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_023799) meningioma expressed antigen 5 (hyaluronidase) [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] meningioma expressed antigen 5 (hyaluronidase) [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Bifunctional protein NCOAT (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (Meningioma-expressed antigen 5) [Includes: Beta-hexosaminidase (N-acetyl-beta-glucosaminidase) (Beta-N-acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D-glucosamin [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Meningioma expressed antigen 5 (hyaluronidase) [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cytosolic beta-N-acetylglucosaminidase [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Mgea5 Isoform 1 of Bifunctional protein NCOAT [mouse-ipi-250309-contam.fasta] bifunctional protein NCOAT [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00655175.2\|SWISS-PROT:Q9EQQ9-1\|TREMBL:Q05CX1;Q9CU60\|ENSEMBL:ENSMUSP00000026243\|REFSEQ:NP_076288 Tax_Id=10090 Gene_Symbol=Mgea5 Isoform 1 of Bifunctional protein NCOAT [ipi.MOUSE.fasta.20090209] Isoform 1 of Bifunctional protein NCOAT OS=Mus musculus GN=Mgea5 [011711_HMR.fasta] sp\|Q9EQQ9\|NCOAT_MOUSE Bifunctional protein NCOAT OS=Mus musculus GN=Mgea5 PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	916 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] cytoplasm [IEA]
Biological Process:	positive regulation of growth hormone secretion [UNKNOWN] negative regulation of protein amino acid glycosylation [UNKNOWN] metabolic process [IEA] positive regulation of calcium ion transport [UNKNOWN] positive regulation of protein complex disassembly [UNKNOWN] positive regulation of glucose import [UNKNOWN] N-acetylglucosamine metabolic process [UNKNOWN] positive regulation of proteolysis [UNKNOWN] protein targeting to membrane [UNKNOWN] necrotic cell death [UNKNOWN] negative regulation of cardiac muscle adaptation [UNKNOWN] positive regulation of DNA metabolic process [UNKNOWN] positive regulation of cell killing [UNKNOWN] positive regulation of mitochondrial depolarization [UNKNOWN] positive regulation of calcium ion transport into cytosol [UNKNOWN] positive regulation of insulin secretion [UNKNOWN] dATP metabolic process [UNKNOWN]
Molecular Function:	histone acetyltransferase activity [UNKNOWN] catalytic activity [IEA] transferase activity [IEA] acyltransferase activity [IEA] beta-N-acetylhexosaminidase activity [IEA] hydrolase activity [IEA] hydrolase activity, acting on glycosyl bonds [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQKESQAAL EERESERNAN PAAASGASLE QSVAPAPGED NPSGAGAAAV VGAAGGARRF  60
   61 LCGVVEGFYG RPWVMEQRKE LFRRLQKWEL NTYLYAPKDD YKHRMFWREM YSVEEAEQLM 120
  121 TLISAAREYE IEFIYAISPG LDITFSNPKE VSTLKRKLDQ VSQFGCRSFA LLFDDIDHNM 180
  181 CAADKEVFSS FAHAQVSITN EIYQYLGEPE TFLFCPTEYC GTFCYPNVSQ SPYLRTVGEK 240
  241 LLPGIEVLWT GPKVVSKEIP VESIEEVSKI IKRAPVIWDN IHANDYDQKR LFLGPYKGRS 300
  301 TELIPRLKGV LTNPNCEFEA NYVAIHTLAT WYKSNMNGVR KDVVMTDSED STVSIQIKLE 360
  361 NEGSDEDIET DVLYSPQMAL KLALTEWLQE FGVPHQYSSR QVAHSGAKTS VVDGTPLVAA 420
  421 PSLNATTVVT TVYQEPIMSQ GAALSGEPSV LTKEEEKKQP DEEPMDMVVE KQEEAEHKND 480
  481 NQILTEIVEA KMAEELRPMD TDKESMAESK SPEMSMQEDC IPDVAPMQTD EQTQKEQFVP 540
  541 GPNEKPLYTA EPVTLEDLQL LADLFYLPYE HGPKGAQMLR EFQWLRANSS VVSVNCKGKD 600
  601 SEKIEEWRSR AAKFEEMCAL VMGMFTRLSN CANRTILYDM YSYVWDIKSI MSMVKSFVQW 660
  661 LGCRSHSSAQ FLIGDQEPWA FRGGLAGEFQ RLLPIDGAND LFFQPPPLTP TSKVYTIRPY 720
  721 FPKDEASVYK ICREMYDDGV GFPFQSQPDL IGDKLVGGLL SLSLDYCFVL EDEDGICGYA 780
  781 LGTVDVTPFI KKCKISWIPF MQEKYTKPNG DKELSEAEKI MLSFHEEQEV LPETFLANFP 840
  841 SLIKMDIHKK VTDPSVAKSM MACLLSSLKA NGSRGAFCEV RPDDKRILEF YSKLGCFEIA 900
  901 KMEGFPKDVV ILGRSL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: OGA_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: