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Protein Overview: COTL1_MOUSE

General Information:
Name(s) found: COTL1_MOUSE [Swiss-Prot]
Description(s) found:
Found 37 descriptions.
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  • Coactosin-like protein OS=Mus musculus GN=Cotl1 PE=1 SV=3 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 142 amino acids

    Gene Ontology:
    Cellular Component: cytoskeleton [IEA]
    cytoplasm [IEA]
    cellular_component [ND]
    intracellular [IEA]
    Biological Process: biological_process [ND]
    defense response to fungus [IDA]
    Molecular Function: protein binding [IPI]
    actin binding [IDA]
    enzyme binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKIDKEAC RAAYNLVRDD GSAVIWVTFR YDGATIVPGD QGADYQHFIQ QCTDDVRLFA  60
   61 FVRFTTGDAM SKRSKFALIT WIGEDVSGLQ RAKTGTDKTL VKEVVQNFAK EFVISDRKEL 120
  121 EEDFIRSELK KAGGANYDAQ SE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..142] PSI-BLAST 34.69897 Solution structure of Coactosin-like protein (Cofilin family) from Mus Musculus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  7.52071741004022 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  6.04859625643932 bayes_pls_golite062009
  • actin filament binding
    		•  5.45532510538573 bayes_pls_golite062009
  • binding
    		•  2.41877859618486 bayes_pls_golite062009
  • protein binding
    		•  1.87981807141519 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.482954032096802 bayes_pls_golite062009
  • structural molecule activity
    		•  0.391701411061931 bayes_pls_golite062009
  • actin monomer binding
    		•  0.224304003054399 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle