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View Structure Prediction Details

Protein: COTL1_MOUSE
Organism: Mus musculus
Length: 142 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COTL1_MOUSE.

Description E-value Query
Range
Subject
Range
gi|48374972 - gi|48374972|gb|AAT42170.1| putative actin depolymerizing factor [Sorghum bicolor]
161.0 [0..1] [129..332]
ADF1_ARATH - Actin-depolymerizing factor 1 OS=Arabidopsis thaliana GN=ADF1 PE=1 SV=1
gi|195604826 - gi|195604826|gb|ACG24243.1| hypothetical protein [Zea mays]
150.0 [0..1] [130..8]
ADF1_PETHY - Actin-depolymerizing factor 1 OS=Petunia hybrida GN=ADF1 PE=2 SV=1
150.0 [0..1] [130..8]
gi|38564721 - gi|38564721|gb|AAR23800.1| putative actin-depolymerizing factor 2 [Helianthus annuus]
149.0 [0..1] [130..8]
gi|109105452 - gi|109105452|ref|XP_001118077.1| PREDICTED: similar to Cofilin-1 (Cofilin, non-muscle isoform) (18 k...
149.0 [0..1] [135..306]
gi|106879609 - gi|106879609|emb|CAJ38388.1| actin-depolymerizing factor [Plantago major]
149.0 [0..1] [130..8]
gi|84028521 - gi|84028521|gb|ABC49719.1| actin depolymerizing factor-like protein [Arachis hypogaea]
149.0 [0..1] [130..8]
ADF_LILLO - Actin-depolymerizing factor OS=Lilium longiflorum PE=2 SV=1
148.0 [0..1] [129..8]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATKIDKEAC RAAYNLVRDD GSAVIWVTFR YDGATIVPGD QGADYQHFIQ QCTDDVRLFA  60
   61 FVRFTTGDAM SKRSKFALIT WIGEDVSGLQ RAKTGTDKTL VKEVVQNFAK EFVISDRKEL 120
  121 EEDFIRSELK KAGGANYDAQ SE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.69897
Match: 1udmA
Description: Solution structure of Coactosin-like protein (Cofilin family) from Mus Musculus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 7.52071741004022 bayes_pls_golite062009
cytoskeletal protein binding 6.04859625643932 bayes_pls_golite062009
actin filament binding 5.45532510538573 bayes_pls_golite062009
binding 2.41877859618486 bayes_pls_golite062009
protein binding 1.87981807141519 bayes_pls_golite062009
structural constituent of cytoskeleton 0.482954032096802 bayes_pls_golite062009
structural molecule activity 0.391701411061931 bayes_pls_golite062009
actin monomer binding 0.224304003054399 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle