Protein Overview: HME2_MOUSE

General Information:
Name(s) found:	HME2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|74180500\|dbj\|BAE34186.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|6753752\|ref\|NP_034264.1\| engrailed 2 [Mus musculus] [NCBI NR] pir\|\|D48423 homeotic protein engrailed 2 - mouse [NCBI NR] gi\|462295\|sp\|P09066.2\|HME2_MOUSE RecName: Full=Homeobox protein engrailed-2; Short=Mo-En-2 [NCBI NR] gi\|293342\|gb\|AAA53527.1\| engrailed protein [Mus musculus] [NCBI NR] gi\|148705280\|gb\|EDL37227.1\| engrailed 2 [Mus musculus] [NCBI NR] Homeobox protein engrailed-2 OS=Mus musculus GN=En2 PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):5-26384915 Homeobox protein engrailed-2 [hmr_yeast5_DM3-1_pombe.fasta] engrailed 2 [HMR_022704-rand.fasta] Homeobox protein engrailed-2 [ipi.MOUSE.v3.06.fasta] engrailed 2 [Mus musculus]gi\|462295\|sp\|P09066\|HME2_MOUSE Homeobox protein engrailed-2 (Mo-En-2)gi\|483210\|pir\|\|D48423 homeotic protein engrailed 2 - mousegi\|293342\|gb\|AAA53527.1\| engrailed protein [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Homeobox protein engrailed-2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_010134) engrailed 2 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] engrailed 2 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Homeobox protein engrailed-2 (Mo-En-2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] engrailed protein [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 HOMEOBOX PROTEIN ENGRAILED-2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=En2 Homeobox protein engrailed-2 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=En2 Homeobox protein engrailed-2 ENSMUSG00000039095 IPI00132513 [IPIxENS.MOUSE_plus_REVERSE.fasta] homeobox protein engrailed-2 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00132513.1\|SWISS-PROT:P09066\|TREMBL:Q3TZM2\|ENSEMBL:ENSMUSP00000036761\|REFSEQ:NP_034264 Tax_Id=10090 Gene_Symbol=En2 Homeobox protein engrailed-2 [ipi.MOUSE.fasta.20090209] Homeobox protein engrailed-2 OS=Mus musculus GN=En2 [011711_HMR.fasta] sp\|P09066\|HME2_MOUSE Homeobox protein engrailed-2 OS=Mus musculus GN=En2 PE=2 SV=2 [uniprot.sptr.mouse.20130102] tr\|Q3TZM2\|Q3TZM2_MOUSE Engrailed 2 OS=Mus musculus GN=En2 PE=2 SV=1 [uniprot.sptr.mouse.20130102] Engrailed 2 OS=Mus musculus GN=En2 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta] Homeobox protein engrailed OS=Mus musculus GN=En2 PE=2 SV=1 [mouse-uniprot-oct2014-contam.fasta] Isoform of P09066, Homeobox protein engrailed-like OS=Mus musculus GN=En2 PE=1 SV=1 [MOUSE.fasta.20160308]
Organism:	Mus musculus
Length:	324 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA]
Biological Process:	midbrain development [IGI] multicellular organismal development [IEA] neuron differentiation [IGI] hindbrain development [IGI] regulation of transcription, DNA-dependent [IEA] neuron development [IGI] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [IDA]
Molecular Function:	DNA binding [IEA] transcription factor activity [IEA] transcription regulator activity [IEA] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEKDSKPSE TAAEAQRQPE PSSGGGSGGG SSPSDSDTGR RRALMLPEVL QAPGNHQHPH  60
   61 RITNFFIDNI LRPEFGRRKD AGTCCAGAGG ARGGEGGAGT TEGGGGGAGG AEQLLGARES 120
  121 RPNPACAPSA GGTLSAAAGD PAVDGEGGSK TLSLHGGAKK PGDPGGSLDG VLKARGLGGG 180
  181 DLSVSSDSDS SQASATLGAQ PMLWPAWVYC TRYSDRPSSG PRSRKPKKKN PNKEDKRPRT 240
  241 AFTAEQLQRL KAEFQTNRYL TEQRRQSLAQ ELSLNESQIK IWFQNKRAKI KKATGNKNTL 300
  301 AVHLMAQGLY NHSTTAKEGK SDSE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: HME2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: