Protein Overview: RPE65_MOUSE, RP6...

General Information:
Name(s) found:	RPE65_MOUSE [Swiss-Prot] RP65_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|48474921\|sp\|Q91ZQ5.3\|RPE65_MOUSE RecName: Full=Retinal pigment epithelium-specific 65 kDa protein [NCBI NR] gi\|19920338\|ref\|NP_084263.1\| retinal pigment epithelium 65 [Mus musculus] [NCBI NR] gi\|15488446\|gb\|AAL01119.1\|AF410461_1 RPE65 [Mus musculus] [NCBI NR] gi\|148679895\|gb\|EDL11842.1\| retinal pigment epithelium 65 [Mus musculus] [NCBI NR] gi\|120537934\|gb\|AAI30029.1\| Retinal pigment epithelium 65 [Mus musculus] [NCBI NR] Retinoid isomerohydrolase OS=Mus musculus GN=Rpe65 PE=1 SV=3 [Swiss-Prot] (Q91ZQ5) Retinal pigment epithelium-specific 65 kDa protein [Swiss-Prot] Ensembl_locations(Chr-bp):3-160326568 RPE65 [hmr_yeast5_DM3-1_pombe.fasta] retinal pigment epithelium 65; retinal pigment epithelium, 65 kDa [HMR_022704-rand.fasta] retinal pigment epithelium 65; retinal pigment epithelium, 65 kDa; modifier of retinal degeneration 1 [071204_hmrz_cont.fasta] retinal pigment epithelium 65 [Mus musculus]gi\|15488446\|gb\|AAL01119.1\| RPE65 [Mus musculus]gi\|48474921\|sp\|Q91ZQ5\|RP65_MOUSE Retinal pigment epithelium-specific 65 kDa protein [nrdb_11152004_Chlamydomonas] (NM_029987) retinal pigment epithelium, 65 kDa [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] retinal pigment epithelium 65 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Retinal pigment epithelium-specific 65 kDa protein [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Retinal pigment epithelium 65 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] RPE65 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 RETINAL PIGMENT EPITHELIUM-SPECIFIC 65 KDA PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Rpe65 Retinal pigment epithelium-specific 65 kDa protein [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Rpe65 Retinal pigment epithelium-specific 65 kDa protein ENSMUSG00000028174 IPI00131304 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00131304.3\|SWISS-PROT:Q91ZQ5\|TREMBL:A1L3D1;Q9CTP3\|ENSEMBL:ENSMUSP00000029824\|REFSEQ:NP_084263 Tax_Id=10090 Gene_Symbol=Rpe65 Retinal pigment epithelium-specific 65 kDa protein [ipi.MOUSE.fasta.20090209] Retinoid isomerohydrolase OS=Mus musculus GN=Rpe65 [011711_HMR.fasta] Tax_Id=10090 Gene_Symbol=Rpe65 Retinoid isomerohydrolase [EBI-IPI_mouse_2_08-18-2011_reversed.fasta] sp\|Q91ZQ5\|RPE65_MOUSE Retinoid isomerohydrolase OS=Mus musculus GN=Rpe65 PE=1 SV=3 [uniprot.sptr.mouse.20130102] tr\|A1L3D1\|A1L3D1_MOUSE Retinal pigment epithelium 65 OS=Mus musculus GN=Rpe65 PE=2 SV=1 [uniprot.sptr.mouse.20130102] Retinal pigment epithelium 65 OS=Mus musculus GN=Rpe65 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
Organism:	Mus musculus
Length:	533 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA] membrane [IEA] plasma membrane [IEA]
Biological Process:	insulin receptor signaling pathway [IMP] retinal metabolic process [IMP] visual perception [IMP] response to stimulus [IEA] regulation of rhodopsin gene expression [IMP]
Molecular Function:	retinal isomerase activity [IMP] retinol isomerase activity [IEA] metal ion binding [IEA] all-trans-retinyl-palmitate hydrolase activity [IEA] hydrolase activity [IEA] isomerase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIQIEHPAG GYKKLFETVE ELSSPLTAHV TGRIPLWLTG SLLRCGPGLF EVGSEPFYHL  60
   61 FDGQALLHKF DFKEGHVTYH RRFIRTDAYV RAMTEKRIVI TEFGTCAFPD PCKNIFSRFF 120
  121 SYFKGVEVTD NALVNIYPVG EDYYACTETN FITKINPETL ETIKQVDLCN YISVNGATAH 180
  181 PHIESDGTVY NIGNCFGKNF TVAYNIIKIP PLKADKEDPI NKSEVVVQFP CSDRFKPSYV 240
  241 HSFGLTPNYI VFVETPVKIN LFKFLSSWSL WGANYMDCFE SNESMGVWLH VADKKRRKYF 300
  301 NNKYRTSPFN LFHHINTYED NGFLIVDLCC WKGFEFVYNY LYLANLRENW EEVKRNAMKA 360
  361 PQPEVRRYVL PLTIDKVDTG RNLVTLPHTT ATATLRSDET IWLEPEVLFS GPRQAFEFPQ 420
  421 INYQKFGGKP YTYAYGLGLN HFVPDKLCKL NVKTKEIWMW QEPDSYPSEP IFVSQPDALE 480
  481 EDDGVVLSVV VSPGAGQKPA YLLVLNAKDL SEIARAEVET NIPVTFHGLF KRS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: RPE65_MOUSE, RP6...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: