Protein Overview: KPYM_MOUSE

General Information:
Name(s) found:	KPYM_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|74223234\|dbj\|BAE40751.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|74183114\|dbj\|BAE22519.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|66267516\|gb\|AAH94663.1\| Pyruvate kinase, muscle [Mus musculus] [NCBI NR] gi\|31981562\|ref\|NP_035229.2\| pyruvate kinase, muscle [Mus musculus] [NCBI NR] gi\|16741633\|gb\|AAH16619.1\| Pyruvate kinase, muscle [Mus musculus] [NCBI NR] gi\|148694031\|gb\|EDL25978.1\| mCG22639 [Mus musculus] [NCBI NR] gi\|146345448\|sp\|P52480.4\|KPYM_MOUSE RecName: Full=Pyruvate kinase isozymes M1/M2; AltName: Full=Pyruvate kinase muscle isozyme [NCBI NR] Pyruvate kinase PKM OS=Mus musculus GN=Pkm PE=1 SV=4 [Swiss-Prot] Ensembl_locations(Chr-bp):9-59838849 Pyruvate kinase 3 [hmr_yeast5_DM3-1_pombe.fasta] pyruvate kinase 3 [HMR_022704-rand.fasta] Pyruvate kinase 3 [ipi.MOUSE.v3.06.fasta] pyruvate kinase 3 [Mus musculus]gi\|16741633\|gb\|AAH16619.1\| Pyruvate kinase 3 [Mus musculus] [nrdb_11152004_Chlamydomonas] pyruvate kinase 3 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 Pyruvate kinase 3 [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] Pyruvate kinase isozymes M1/M2 (Pyruvate kinase muscle isozyme) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] pyruvate kinase, muscle [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mCG22639 [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Pyruvate kinase, muscle [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 PYRUVATE KINASE 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Pkm2 Isoform M2 of Pyruvate kinase isozymes M1/M2 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Pkm2 Isoform M2 of Pyruvate kinase isozymes M1/M2 ENSMUSG00000032294 IPI00407130 IPI00845840 [IPIxENS.MOUSE_plus_REVERSE.fasta] pyruvate kinase isozymes M1/M2 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00407130.4\|SWISS-PROT:P52480-1\|ENSEMBL:ENSMUSP00000034834\|REFSEQ:NP_035229 Tax_Id=10090 Gene_Symbol=Pkm2 Isoform M2 of Pyruvate kinase isozymes M1/M2 [ipi.MOUSE.fasta.20090209] Isoform M2 of Pyruvate kinase isozymes M1/M2 OS=Mus musculus GN=Pkm2 [011711_HMR.fasta] Pyruvate kinase isozymes M1/M2 OS=Mus musculus GN=Pkm2 PE=1 SV=4 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta] Pyruvate kinase isozymes M1/M2 OS=Mus musculus GN=Pkm PE=1 SV=4 [121003-MOUSE.fasta] sp\|P52480\|KPYM_MOUSE Pyruvate kinase isozymes M1/M2 OS=Mus musculus GN=Pkm PE=1 SV=4 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	531 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] soluble fraction [UNKNOWN] cytoplasm [IEA] mitochondrion [IDA] flagellum [IDA]
Biological Process:	pyruvate biosynthetic process [UNKNOWN] liver development [UNKNOWN] glycolysis [UNKNOWN][IDA] organ regeneration [UNKNOWN] glucose metabolic process [UNKNOWN] ATP biosynthetic process [UNKNOWN] skeletal muscle tissue regeneration [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] magnesium ion binding [IEA] ATP binding [IEA] pyruvate kinase activity [UNKNOWN][IDA] potassium ion binding [IEA] protein binding [IPI] metal ion binding [IEA] catalytic activity [IEA] ADP binding [UNKNOWN] transferase activity [IEA] kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKPHSEAGT AFIQTQQLHA AMADTFLEHM CRLDIDSAPI TARNTGIICT IGPASRSVEM  60
   61 LKEMIKSGMN VARLNFSHGT HEYHAETIKN VREATESFAS DPILYRPVAV ALDTKGPEIR 120
  121 TGLIKGSGTA EVELKKGATL KITLDNAYME KCDENILWLD YKNICKVVEV GSKIYVDDGL 180
  181 ISLQVKEKGA DFLVTEVENG GSLGSKKGVN LPGAAVDLPA VSEKDIQDLK FGVEQDVDMV 240
  241 FASFIRKAAD VHEVRKVLGE KGKNIKIISK IENHEGVRRF DEILEASDGI MVARGDLGIE 300
  301 IPAEKVFLAQ KMMIGRCNRA GKPVICATQM LESMIKKPRP TRAEGSDVAN AVLDGADCIM 360
  361 LSGETAKGDY PLEAVRMQHL IAREAEAAIY HLQLFEELRR LAPITSDPTE AAAVGAVEAS 420
  421 FKCCSGAIIV LTKSGRSAHQ VARYRPRAPI IAVTRNPQTA RQAHLYRGIF PVLCKDAVLN 480
  481 AWAEDVDLRV NLAMDVGKAR GFFKKGDVVI VLTGWRPGSG FTNTMRVVPV P

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.66

Protein Overview: KPYM_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: