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Protein Overview: NOP2_SCHPO

General Information:
Name(s) found: NOP2_SCHPO [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • 25S rRNA (cytosine-C(5))-methyltransferase nop2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nop2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Schizosaccharomyces pombe 972h-
    Length: 608 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRKQKSKQG IPPTLEENHN SSHKVTENAK KRKHSKEKPQ NSRKRQLAEE KKSLFENSDS  60
   61 ENEKDLIDAD EFEEAETLSD LEHDEEPQTF ADEFIDDEAK ECEGEEEDSV FDSDEEHEVK 120
  121 PMFSDDSGDE EDLELANMEA MSRKLDEEAE LEEKEAEEEL HTNIHPEAPT VLPPIDGFTD 180
  181 SQPISTLPQD LSQIQLRIQE IVRVLNDFKN LCEPGRNRSE YVDQLLNDIC AYYGYSRFLA 240
  241 EKLFELFSVS EAVEFFEANE MPRPVTIRTN TLKTQRRELA QALINRGVNL EPIGKWSKVG 300
  301 LQVFESQVPI GATPEYLAGH YILQAASSFL PVMALAPQPN ERILDMSSAP GGKVTYVAAL 360
  361 QKNTGIIFAN DSNKARTKAL SANIHRLGVR NAIVCNYDGR KFPNEVIGGF DRVLLDAPCS 420
  421 GTGVIYKDQS VKTNKSERDF DTLSHLQRQL LLSAIDSVNA DSKTGGFIVY STCSITVDED 480
  481 EAVIQYALKK RPNVKLVSTG LEFGREGFTR FREKRFHPSL KLTRRYYPHV HNIDGFFVAK 540
  541 LKKISDKIPT VNVADDMKDG TNNDVEIEKN STEIDNITFN DEADKEIIEQ NRRKWLKSKG 600
  601 YKVAKKKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..145] MSA 17.231997 View MSA. No confident structure predictions are available.
    2 View Details [146..545] PSI-BLAST 55.0 The crystal structure of E. coli Fmu binary complex with S-Adenosylmethionine at 2.1 A resolution
    3 View Details [546..608] PSI-BLAST 62.045757 No description for 2frxA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  4.09362182773099 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  4.07806017452628 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  3.92746815303714 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.39429041855776 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  3.07428840534971 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  2.99461585647365 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  2.43145108778901 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  2.41876112831625 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  2.41876112831625 bayes_pls_golite062009
  • transferase activity
    		•  2.22303238506686 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  2.04296107639729 bayes_pls_golite062009
  • rRNA (guanine) methyltransferase activity
    		•  2.00108769169811 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  1.83964463328968 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  1.76571145896453 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  1.75675289134467 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  1.66871163498737 bayes_pls_golite062009
  • transcription termination factor activity
    		•  1.58162486937564 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  1.1103522853299 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.914549843668268 bayes_pls_golite062009
  • rRNA (uridine-2'-O-)-methyltransferase activity
    		•  0.90544396691236 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  0.89325812193225 bayes_pls_golite062009
  • DNA binding
    		•  0.86027591375666 bayes_pls_golite062009
  • rRNA (uridine) methyltransferase activity
    		•  0.742142092552002 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.703178429468566 bayes_pls_golite062009
  • tRNA (cytosine-5-)-methyltransferase activity
    		•  0.672282175551951 bayes_pls_golite062009
  • tRNA (cytosine)-methyltransferase activity
    		•  0.672282175551951 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.616949327277483 bayes_pls_golite062009
  • RNA binding
    		•  0.417524996559564 bayes_pls_golite062009
  • binding
    		•  0.383237930789959 bayes_pls_golite062009
  • O-methyltransferase activity
    		•  0.250946859465502 bayes_pls_golite062009
  • tRNA (adenine-N1-)-methyltransferase activity
    		•  0.0803947886180681 bayes_pls_golite062009
  • tRNA (adenine)-methyltransferase activity
    		•  0.0803947886180681 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle