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Protein Overview: gi|108807225, gi...

General Information:
Name(s) found: gi|108807225 [NCBI NR]
gi|108779138 [NCBI NR]
Description(s) found:
Found 3 descriptions.
SHOW ALL
  • gi|108807225|ref|YP_651141.1| trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase [Yersinia pestis Antiqua] [NCBI NR]
  • gi|108779138|gb|ABG13196.1| L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase [Yersinia pestis Antiqua] [NCBI NR]
    • Organism: Yersinia pestis Antiqua
    Length: 1323 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANTTMGVKL DEATRDRIKS AAQRIDRTPH WLIKQAIFNY LEKLESNSEL PELATTSSLS  60
   61 LQDTEDAIPQ LTENTHQPFL DFAEHVLPQS VTRAAITAAY RRPETEAIPM LLEQARLPAD 120
  121 LAQATHKLAY SIAEKLRNQK SAHGRAGMVQ GLLQEFSLSS QEGVALMCLA EALLRIPDKP 180
  181 TRDALIRDKI SNGNWHSHLG RSPSMFVNAA TWGLLFTGRL VSTHNEAKLS GSLNRIIGKG 240
  241 GEPLIRKGVD MAMRLMGEQF VTGETISEAL ANARKLEDKG FRYSYDMLGE AALTEADAQA 300
  301 YLLSYQQAIH AIGKASNGRG IYEGPGISIK LSALHPRYSR AQYERVMDEL YPRLLSLTLQ 360
  361 ARQYDIGINI DAEEADRLEI SLDLLERLCF EPQLAGWNGI GFVIQAYQKR CPSTIDAVID 420
  421 MAQRSRRRLM IRLVKGAYWD SEIKRAQIDG LEGYPVYTRK VYTDVSYLAC ARKLLAVPNL 480
  481 IYPQFATHNA HTLSAIYHLA GQNYYPGQYE FQCLHGMGEP LYEQVVGKVA EGKLNRPCRI 540
  541 YAPVGTHETL LAYLVRRLLE NGANTSFVNR IADATLPLDE LVADPVSAVE AMAAAEGQLG 600
  601 LPHPRIPLPR ELFGKDRANS SGVDLANEHR LASLSSALLA SASQVWRAEP VIDAEQDNGD 660
  661 ALPVINPAEP ADVVGYVREA TEGEVSRALD AAARAGAIWF ATPPAERAAI LIRAAELMEN 720
  721 QMQTLMGILV REAGKTFSNA IAEVREAVDF LHYYAGIVRD NFANDSHRPL GPVVCISPWN 780
  781 FPLAIFTGQV AAALAAGNSV LAKPAEQTPL IAAQAVRILL DAGIPQGVLQ LLPGRGDSVG 840
  841 ALLVNDARVR AVMFTGSTEV ATILQRSIAG RLDPQGRPTP LIAETGGLNA MIVDSSALTE 900
  901 QVVTDVVASA FDSAGQRCSA LRILCIQDDV AEHTLQMLRG AMAECRMGNP ERLSTDIGPV 960
  961 IDAEAKTGIE RHIQAMRAKG RKVYQAARTN SLDEKEWQRG TFIKPTLIEL DSFDELQKEV1020
 1021 FGPVLHVVRF QRQHLNELVD QINASGYGLT LGIHTRIDET IARVTEKAKV GNLYVNRNMV1080
 1081 GAVVGVQPFG GEGLSGTGPK AGGPLYLYRL LSSRPDDALA NTLAHQDGEQ QQNVAGREAL1140
 1141 LTAHRAFTQW ATEQQHDSLA TLCQRYASLA QGGTVRLLPG PTGERNTYAL LPRERVLCLA1200
 1201 DTESDTLTQL AAVLATGSQV LWPENDVQKA LLPQLPTEVQ SRITLTHDWQ TANITFDAVI1260
 1261 YHGDADQLRT LCEQVAQIDG PIVSVQGFAR GETNILLERL LIEHSLSVNT AAAGGNASLM1320
 1321 TIG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..651] PSI-BLAST 1000.0 N-terminal domain of bifunctional PutA protein; Proline dehydrohenase domain of bifunctional PutA protein
    2 View Details [652..1124] PSI-BLAST 150.0 Aldehyde reductase (dehydrogenase), ALDH
    3 View Details [1125..1323] FFAS03 3.9 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  6.88732579226533 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  5.85999181868044 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  5.85251457886657 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.26500423104107 bayes_pls_golite062009
  • catalytic activity
    		•  2.15527229494088 bayes_pls_golite062009
  • binding
    		•  1.75614413431284 bayes_pls_golite062009
  • methylenetetrahydrofolate reductase (NADPH) activity
    		•  1.53575450131902 bayes_pls_golite062009
  • protein binding
    		•  1.38007868564575 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.577994923694075 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.464400793583132 bayes_pls_golite062009
  • DNA binding
    		•  0.359090400165996 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.0464200104039556 bayes_pls_golite062009
    2
    Term Confidence Notes
  • oxidoreductase activity
    		•  4.47226217021998 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  4.34495776828926 bayes_pls_golite062009
  • methylmalonate-semialdehyde dehydrogenase (acylating) activity
    		•  3.87605237828483 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase [NAD(P)+] activity
    		•  3.64672165191647 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  3.52624358965579 bayes_pls_golite062009
  • 3-chloroallyl aldehyde dehydrogenase activity
    		•  3.37049090049734 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  3.2867555127991 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  2.99564252244797 bayes_pls_golite062009
  • aldehyde dehydrogenase (NAD) activity
    		•  2.81851373615334 bayes_pls_golite062009
  • catalytic activity
    		•  2.80804701752928 bayes_pls_golite062009
  • glutamate-5-semialdehyde dehydrogenase activity
    		•  2.78416888468693 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase activity
    		•  2.71501590413507 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  2.70230501280821 bayes_pls_golite062009
  • aldehyde dehydrogenase [NAD(P)+] activity
    		•  2.43250909158896 bayes_pls_golite062009
  • malonate-semialdehyde dehydrogenase (acetylating) activity
    		•  1.75951883819887 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  1.6559690223037 bayes_pls_golite062009
  • retinal dehydrogenase activity
    		•  1.42867174920845 bayes_pls_golite062009
  • binding
    		•  1.06673666884196 bayes_pls_golite062009
  • protein binding
    		•  0.894945263794726 bayes_pls_golite062009
  • histidinol dehydrogenase activity
    		•  0.258030369394064 bayes_pls_golite062009
  • benzaldehyde dehydrogenase (NAD+) activity
    		•  0.23487570676521 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle