Protein Overview: ASAH2_MOUSE

General Information:
Name(s) found:	ASAH2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9055168\|ref\|NP_061300.1\| N-acylsphingosine amidohydrolase 2 [Mus musculus] [NCBI NR] gi\|81868467\|sp\|Q9JHE3.1\|ASAH2_MOUSE RecName: Full=Neutral ceramidase; Short=N-CDase; Short=NCDase; AltName: Full=Acylsphingosine deacylase 2; AltName: Full=N-acylsphingosine amidohydrolase 2; Contains: RecName: Full=Neutral ceramidase soluble form [NCBI NR] gi\|7576311\|dbj\|BAA94546.1\| nerutal ceramidase [Mus musculus] [NCBI NR] gi\|7576309\|dbj\|BAA94545.1\| neutral ceramidase [Mus musculus] [NCBI NR] gi\|223459842\|gb\|AAI37899.1\| N-acylsphingosine amidohydrolase 2 [Mus musculus] [NCBI NR] gi\|148709771\|gb\|EDL41717.1\| N-acylsphingosine amidohydrolase 2, isoform CRA_b [Mus musculus] [NCBI NR] Neutral ceramidase OS=Mus musculus GN=Asah2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):19-31395458;19-31395458 Nerutal ceramidase [hmr_yeast5_DM3-1_pombe.fasta] N-acylsphingosine amidohydrolase 2; neutral/alkaline; neutral/alkaline ceramidase [HMR_022704-rand.fasta] N-acylsphingosine amidohydrolase 2 [Mus musculus]gi\|7576311\|dbj\|BAA94546.1\| nerutal ceramidase [Mus musculus]gi\|7576309\|dbj\|BAA94545.1\| neutral ceramidase [Mus musculus] [nrdb_11152004_Chlamydomonas] (NM_018830) N-acylsphingosine amidohydrolase 2; neutral/alkaline; neutral/alkaline ceramidase [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] N-acylsphingosine amidohydrolase 2 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Neutral ceramidase (N-CDase) (NCDase) (Acylsphingosine deacylase 2) (N-acylsphingosine amidohydrolase 2) [Contains: Neutral ceramidase soluble form] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] N-acylsphingosine amidohydrolase 2, isoform CRA_b [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] nerutal ceramidase [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] neutral ceramidase [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Asah2 Neutral ceramidase [mouse-ipi-250309-contam.fasta] Neutral ceramidase (NCDase) (N-CDase) (Acylsphingosine deacylase 2) (N-acylsphingosine amidohydrolase 2) [Contains: Neutral ceramidase soluble form] [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Asah2 Neutral ceramidase ENSMUSG00000024887 IPI00458077 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00458077.2\|SWISS-PROT:Q9JHE3\|ENSEMBL:ENSMUSP00000093830;ENSMUSP00000108146\|REFSEQ:NP_061300 Tax_Id=10090 Gene_Symbol=Asah2 Neutral ceramidase [ipi.MOUSE.fasta.20090209] Neutral ceramidase OS=Mus musculus GN=Asah2 [011711_HMR.fasta] sp\|Q9JHE3\|ASAH2_MOUSE Neutral ceramidase OS=Mus musculus GN=Asah2 PE=1 SV=1 [uniprot.sptr.mouse.20130102] tr\|B9EHG7\|B9EHG7_MOUSE N-acylsphingosine amidohydrolase 2 OS=Mus musculus GN=Asah2 PE=2 SV=1 [uniprot.sptr.mouse.20130102] N-acylsphingosine amidohydrolase 2 OS=Mus musculus GN=Asah2 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta] Isoform of Q9JHE3, N-acylsphingosine amidohydrolase 2 OS=Mus musculus GN=Asah2 PE=1 SV=1 [MOUSE.fasta.20160308]
Organism:	Mus musculus
Length:	756 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] membrane [IEA] mitochondrion [IDA] integral to membrane [IEA] plasma membrane [IEA]
Biological Process:	cell proliferation [TAS] response to organic substance [UNKNOWN] apoptosis [IEA] lipid metabolic process [IEA] sphingolipid metabolic process [IEA]
Molecular Function:	ceramidase activity [IDA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKRTFSTLE AFLIFLLVIM TVITVALLTL LFVTSGTIEN HKDSGNHWFS TTLGSTTTQP  60
   61 PPITQTPNFP SFRNFSGYYI GVGRADCTGQ VSDINLMGYG KNGQNARGLL TRLFSRAFIL 120
  121 ADPDGSNRMA FVSVELCMIS QRLRLEVLKR LESKYGSLYR RDNVILSAIH THSGPAGFFQ 180
  181 YTLYILASEG FSNRTFQYIV SGIMKSIDIA HTNLKPGKIF INKGNVANVQ INRSPSSYLL 240
  241 NPQSERARYS SNTDKEMLVL KLVDLNGEDL GLISWFAIHP VSMNNSNHFV NSDNMGYAAY 300
  301 LFEQEKNKGY LPGQGPFVAG FASSNLGDVS PNILGPHCVN TGESCDNDKS TCPNGGPSMC 360
  361 MASGPGQDMF ESTHIIGRII YQKAKELYAS ASQEVTGPVL AAHQWVNMTD VSVQLNATHT 420
  421 VKTCKPALGY SFAAGTIDGV SGLNITQGTT EGDPFWDTLR DQLLGKPSEE IVECQKPKPI 480
  481 LLHSGELTIP HPWQPDIVDV QIVTVGSLAI AAIPGELTTM SGRRFREAIK KEFALYGMKD 540
  541 MTVVIAGLSN VYTHYITTYE EYQAQRYEAA STIYGPHTLS AYIQLFRDLA KAIATDTVAN 600
  601 MSSGPEPPFF KNLIASLIPN IADRAPIGKH FGDVLQPAKP EYRVGEVVEV IFVGANPKNS 660
  661 AENQTHQTFL TVEKYEDSVA DWQIMYNDAS WETRFYWHKG ILGLSNATIY WHIPDTAYPG 720
  721 IYRIRYFGHN RKQELLKPAV ILAFEGISSP FEVVTT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ASAH2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: